loading...| Preferred Name |
Lipoprotein associated phospholipase A2 |
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| Synonyms |
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| ID |
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571347974240596158 |
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| rdfs:comment |
Biomarkers of ischemic stroke |
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| altLabel |
Platelet-activating factor acetylhydrolase PAF acetylhydrolase Lp-PLA2 LDL-PLA2 Lipoprotein-associated phospholipase A2 PLA2G7 LDL-associated phospholipase A2 |
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| dc:source | ||
| definition |
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA. |
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| label |
Lipoprotein associated phospholipase A2 |
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| oboInOwl:hasDbXref | ||
| prefLabel |
Lipoprotein associated phospholipase A2 |
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| subClassOf |
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571347974240596018 |