Preferred Name

professional antigen presenting cell
Synonyms

APC

Definitions

A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as constimulatory molecules, and thus can initiate immune responses via T cells.

ID

http://purl.obolibrary.org/obo/ZFA_0009088

comment

Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as constimulatory molecules, and thus can initiate immune responses via T cells.

database_cross_reference

TAO:0009088

CL:0000145

definition

A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.

end stage

http://purl.obolibrary.org/obo/ZFS_0000044

has_exact_synonym

APC

has_obo_namespace

zebrafish_anatomy

id

ZFA:0009088

in_subset

http://purl.obolibrary.org/obo/zfa#cell_slim

label

professional antigen presenting cell

notation

ZFA:0009088

prefLabel

professional antigen presenting cell

start stage

http://purl.obolibrary.org/obo/ZFS_0000000

treeView

http://purl.obolibrary.org/obo/ZFA_0009309

subClassOf

http://purl.obolibrary.org/obo/ZFA_0009309

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