Preferred Name | dendritic cell tumor peptide vaccine | |
Synonyms |
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Definitions |
A cancer vaccine composed of dendritic cells pulsed with peptide epitopes that stimulate cytotoxic T lymphocyte anti-tumor activity. This vaccine is used to treat diffuse hemispheric glioma with a H3 G34 mutation that has come back (recurrent) and/or is growing, spreading, or getting worse (progressive). It is made with the patient's own white blood cells and peptide-pulsed dendritic cells, which may help the body build an effective immune response to kill tumor cells. It is combined with immunotherapy monoclonal antibodies, such as nivolumab and ipilimumab, which also may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. |
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ID |
http://purl.obolibrary.org/obo/VO_0007516 |
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definition |
A cancer vaccine composed of dendritic cells pulsed with peptide epitopes that stimulate cytotoxic T lymphocyte anti-tumor activity. This vaccine is used to treat diffuse hemispheric glioma with a H3 G34 mutation that has come back (recurrent) and/or is growing, spreading, or getting worse (progressive). It is made with the patient's own white blood cells and peptide-pulsed dendritic cells, which may help the body build an effective immune response to kill tumor cells. It is combined with immunotherapy monoclonal antibodies, such as nivolumab and ipilimumab, which also may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. |
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definition source |
VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=6282 |
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has function | ||
immunizes against disease | ||
immunizes recipient | ||
label |
dendritic cell tumor peptide vaccine |
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prefixIRI |
VO:0007516 |
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prefLabel |
dendritic cell tumor peptide vaccine |
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status of vaccine development |
Clinical trial |
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term editor |
Hayleigh Kahn Jie Zheng |
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vaccinated in route | ||
VIOLIN vaccine ID |
6282 |
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subClassOf |
http://purl.obolibrary.org/obo/VO_0007657 |
Delete | Mapping To | Ontology | Source |
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1987 | NCIT | LOOM | |
http://purl.obolibrary.org/obo/NCIT_C1987 | BERO | LOOM |