Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

Synonyms

chondrogenic tissue

cartilage tissue

cartilaginous tissue

portion of cartilage tissue

cartilage

cartilages

Definitions

Previous: "A portion of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate[GO]. Regular connective tissue, which consists of chondrocytes and related cells, the intercellular matrix of which is chondrified. Examples: hyaline cartilage, fibrocartilage, elastic cartilage[FMA]. an avascular supporting and articular skeletal tissue. It also functions as the primary endoskeletal support in vertebrate embryos. Cartilage is deposited by and is composed of chondroblasts and chondrocytes separated by an extracellular matrix, which may or may not mineralize depending on cartilage type, age, or taxon[Hall and Witten]." See also FMA:71500 Set of cartilages, FMA:55107 Cartilage organ, FMA:12264 Articular cartilage. // elements made from cartilage, cartilage-like, or chondroid tissues evolved in invertebrates[H&W] Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts.

ID

http://purl.obolibrary.org/obo/UBERON_0002418

comment

Previous: "A portion of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate[GO]. Regular connective tissue, which consists of chondrocytes and related cells, the intercellular matrix of which is chondrified. Examples: hyaline cartilage, fibrocartilage, elastic cartilage[FMA]. an avascular supporting and articular skeletal tissue. It also functions as the primary endoskeletal support in vertebrate embryos. Cartilage is deposited by and is composed of chondroblasts and chondrocytes separated by an extracellular matrix, which may or may not mineralize depending on cartilage type, age, or taxon[Hall and Witten]." See also FMA:71500 Set of cartilages, FMA:55107 Cartilage organ, FMA:12264 Articular cartilage. // elements made from cartilage, cartilage-like, or chondroid tissues evolved in invertebrates[H&W]

contributes to morphology of

http://purl.obolibrary.org/obo/UBERON_0001434

contributor

https://github.com/cmungall

https://github.com/mellybelly

database_cross_reference

SCTID:309312004

galen:Cartilage

AEO:0000087

TAO:0001501

UMLS:C0007301

Wikipedia:Cartilage

VHOG:0001207

AAO:0000060

XAO:0000170

MAT:0000189

BTO:0000206

EHDAA2:0003087

NCIT:C32268

MIAA:0000189

EFO:0000949

MESH:D002356

OpenCyc:Mx4rvVjeOZwpEbGdrcN5Y29ycA

NCIT:C12373

VSAO:0000040

ZFA:0005622

EMAPA:32730

EV:0100141

FMA:37377

GAID:99

MA:0000104

definition

Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts.

depicted_by

http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg

depiction

http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg

has exact synonym

chondrogenic tissue

cartilage tissue

cartilaginous tissue

has part

http://purl.obolibrary.org/obo/CL_0000138

http://purl.obolibrary.org/obo/CHEBI_18085

has related synonym

portion of cartilage tissue

cartilage

cartilages

has_obo_namespace

uberon

id

UBERON:0002418

in_subset

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

cartilage tissue

notation

UBERON:0002418

only in taxon

http://purl.obolibrary.org/obo/NCBITaxon_33213

part_of

http://purl.obolibrary.org/obo/UBERON_0002204

prefixIRI

UBERON:0002418

treeView

http://purl.obolibrary.org/obo/UBERON_0002204

UBPROP_0000001

Portion of tissue which is connective tissue composed of collagen and/or elastin fibers and chondrocytes. Cartilage is avascular and provides both skeletal functions and a framework upon which bone is deposited.[TAO]

Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts.[VSAO]

A type of dense connective tissue. It is composed of cells called chondrocytes which are dispersed in a firm gel-like ground substance, called the matrix. Cartilage is avascular (contains no blood vessels) and nutrients are diffused through the matrix. Cartilage is found in the joints, the rib cage, the ear, the nose, in the throat and between intervertebral disks. It makes up virtually the entire skeleton in chondrichthyes.[AAO]

UBPROP_0000002

relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]

UBPROP_0000003

Phylogenetic analysis suggests that cartilage arose independently in cnidarians, hemichordates, vertebrates, arthropods, annelids, brachiopods, and molluscs - or a common ancestor of brachiopods and molluscs (...). Analyses of cartilage as a tissue and of the development of invertebrate cartilages are consistent with homology between invertebrate and vertebrate cartilage. From the discussion above, it will be clear that understanding genetic changes underlying cartilage evolution is key to determining whether the multiple origins of cartilage represent parallel evolution.[well established][VHOG]

disjointWith

http://purl.obolibrary.org/obo/UBERON_0002481

subClassOf

http://purl.obolibrary.org/obo/UBERON_0004755

http://purl.obolibrary.org/obo/BFO_0000040

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