Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

tectorial membrane of cochlea

Synonyms

tectorial membrane of spiral organ of cochlea

tectorial membrane

Definitions

The overlaying membrane of the cochlear duct, an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells; sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair cell membrane potential, transducing sound into electrical signals[MP,modified].

ID

http://purl.obolibrary.org/obo/UBERON_0002233

attached to

http://purl.obolibrary.org/obo/UBERON_0002276

database_cross_reference

UMLS:C1184928

NCIT:C33740

Wikipedia:Tectorial_membrane_(cochlea)

UMLS:C0039432

SCTID:368960006

BIRNLEX:2531

EMAPA:35851

MESH:D013680

FMA:75805

GAID:876

MA:0001199

definition

The overlaying membrane of the cochlear duct, an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells; sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair cell membrane potential, transducing sound into electrical signals[MP,modified].

has exact synonym

tectorial membrane of spiral organ of cochlea

tectorial membrane

has_obo_namespace

uberon

id

UBERON:0002233

in_subset

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

tectorial membrane of cochlea

notation

UBERON:0002233

part_of

http://purl.obolibrary.org/obo/RO_0002577

http://purl.obolibrary.org/obo/UBERON_0001855

prefixIRI

UBERON:0002233

prefLabel

tectorial membrane of cochlea

treeView

http://purl.obolibrary.org/obo/RO_0002577

http://purl.obolibrary.org/obo/UBERON_0001855

UBPROP_0000001

The tectorial membrane (TM) is one of two acellular gels in the cochlea of the inner ear, the other being the basilar membrane (BM). The TM is located above the sulcus spiralis internus and the spiral organ of Corti and extends along the longitudinal length of the cochlea parallel to the BM. Radially the TM is divided into three zones, the limbal, middle and marginal zones. Of these the limbal zone is the thinnest (transversally) and overlies the auditory teeth of Huschke with its inside edge attached to the spiral limbus. The marginal zone is the thickest (transversally) and is divided from the middle zone by Hensen's Stripe. It overlies the sensory inner hair cells and electrically-motile outer hair cells of the organ of Corti and during acoustic stimulation stimulates the inner hair cells through fluid coupling, and the outer hair cells via direct connection to their tallest stereocilia[Wikipedia:Tectorial_membrane_(cochlea)].

UBPROP_0000008

in some squamate lineages, the tectorial membrane may not cover the whole cochlear duct/papilla. In some lineages, the tectorial membrane is divided into units called sallets[ISBN:9780387714691]

subClassOf

http://purl.obolibrary.org/obo/UBERON_0004121

http://purl.obolibrary.org/obo/UBERON_0005764

http://purl.obolibrary.org/obo/UBERON_0010314

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