loading...| Preferred Name |
nucleus raphe pallidus |
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| Synonyms |
nucleus raphes pallidus pallidal raphe nucleus raphe pallidus nucleus nucleus raphC) pallidus |
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| Definitions |
The nucleus raphe pallidus receives afferent connections from the periaqueductal gray, the paraventricular hypothalamic nucleus, central nucleus of the amygdala, lateral hypothalamic area, and parvocellular reticular nucleus. Also, the pallidus receives afferents from the medial preoptic area, median preoptic nucleus and lateral paragigantocellular reticular nuclei . The pallidus has recently been shown to be involved in the activation of a fever as an immunoreaction. It has been implied that the preoptic area is constantly inhibiting the raphe pallidus, especially the rostral portion, with GABA. When the preoptic area receives immune signals from the body, the inhibition stops and the rostral portion of the raphe pallidus excites the intermediolateral cell column, which induces a fever . The raphe pallidus has also been known to mediate the tachycardia response, an extremely high heart rate known to be incited by emotional or psychological stress. Microinjections of a GABA-a antagonist into the raphe pallidus, induces an increased heart rate. Conversely, microinjections of muscimol, a GABA-a agonist, inhibit tachycardia in rats under air-stress stimuli. In both of these cases, GABA is mediating two different sympathetic responses, so clearly the nucleus raphe pallidus is a far more a complex nucleus than previously thought. [WP,unvetted]. |
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| ID |
http://purl.obolibrary.org/obo/UBERON_0002157 |
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| database_cross_reference |
MESH:D065848 UMLS:C0175517 Wikipedia:Nucleus_raphe_pallidus neuronames:741 EMAPA:35722 BIRNLEX:1375 BAMS:RPA BAMS:RPa DHBA:12644 FMA:72586 HBA:9649 MA:0001051 MBA:230 |
|
| definition |
The nucleus raphe pallidus receives afferent connections from the periaqueductal gray, the paraventricular hypothalamic nucleus, central nucleus of the amygdala, lateral hypothalamic area, and parvocellular reticular nucleus. Also, the pallidus receives afferents from the medial preoptic area, median preoptic nucleus and lateral paragigantocellular reticular nuclei . The pallidus has recently been shown to be involved in the activation of a fever as an immunoreaction. It has been implied that the preoptic area is constantly inhibiting the raphe pallidus, especially the rostral portion, with GABA. When the preoptic area receives immune signals from the body, the inhibition stops and the rostral portion of the raphe pallidus excites the intermediolateral cell column, which induces a fever . The raphe pallidus has also been known to mediate the tachycardia response, an extremely high heart rate known to be incited by emotional or psychological stress. Microinjections of a GABA-a antagonist into the raphe pallidus, induces an increased heart rate. Conversely, microinjections of muscimol, a GABA-a agonist, inhibit tachycardia in rats under air-stress stimuli. In both of these cases, GABA is mediating two different sympathetic responses, so clearly the nucleus raphe pallidus is a far more a complex nucleus than previously thought. [WP,unvetted]. |
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| depiction |
http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png |
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| has exact synonym |
nucleus raphes pallidus pallidal raphe nucleus raphe pallidus nucleus |
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| has related synonym |
nucleus raphes pallidus nucleus raphC) pallidus |
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| has_obo_namespace |
uberon |
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| id |
UBERON:0002157 |
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| in_subset | ||
| label |
nucleus raphe pallidus |
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| notation |
UBERON:0002157 |
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| part_of | ||
| prefixIRI |
UBERON:0002157 |
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| prefLabel |
nucleus raphe pallidus |
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| RO_0002171 | ||
| treeView | ||
| subClassOf |