Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

loop of Henle

Synonyms

Henle's loop

ansa nephroni

Henle loop

Definitions

The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine.

ID

http://purl.obolibrary.org/obo/UBERON_0001288

continuous with

http://purl.obolibrary.org/obo/UBERON_0001292

http://purl.obolibrary.org/obo/UBERON_0001287

contributes to morphology of

http://purl.obolibrary.org/obo/UBERON_0001231

database_cross_reference

Wikipedia:Loop_of_Henle

SCTID:361335009

VHOG:0001270

EMAPA:19280

UMLS:C0023986

MESH:D008138

BTO:0004608

NCIT:C33006

EV:0100390

FMA:17698

GAID:437

MA:0001675

definition

The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine.

depiction

http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png

editor note

the definitions of some kidney parts (e.g. proximal straight tubule) refer to Henle's loop, even in species where this may not be present. Requires review.

has exact synonym

Henle's loop

ansa nephroni

Henle loop

has_obo_namespace

uberon

id

UBERON:0001288

in_subset

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

loop of Henle

notation

UBERON:0001288

prefixIRI

UBERON:0001288

prefLabel

loop of Henle

RO_0002174

http://purl.obolibrary.org/obo/NCBITaxon_8353

RO_0002175

http://purl.obolibrary.org/obo/NCBITaxon_8782

UBPROP_0000001

A highly specialized segment of the mammalian kidney tubules, that dips into the medulla. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Grande_L, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF, p.648, see_Liem_KF][VHOG]

UBPROP_0000008

The structure differs considerably between species; there is a definite physical loop of Henle in the mammalian and avian renal systems but this seems to be absent in Xenopus. However, homologs of some, but not all, molecular markers (e.g. cldn8 and clcnk) of the mammalian loop of Henle were found to be present in the pronephros of the frog larva .

UBPROP_0000009

The loop of Henle plays an important role in creating a concentration gradient in the medulla of the kidney. It is involved in reabsorption of filtered water and ions including sodium, potassium and calcium, and independently regulates both the volume and osmolarity of body fluids.

subClassOf

http://purl.obolibrary.org/obo/UBERON_0007685

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/UBERON_0001288 UBERON SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001288 OBA SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001288 CL SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001288 EFO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001288 BERO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001288 HHEAR SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001288 OBA SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001288 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001288 KTAO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001288 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001288 FNS-H SAME_URI
http://purl.obolibrary.org/obo/UBERON_0001288 UBERON LOOM
http://purl.obolibrary.org/obo/UBERON_0001288 OBA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A05.810.453.736.560.610 RH-MESH LOOM
http://purl.obolibrary.org/obo/EMAPA_19280 EMAPA LOOM
http://www.co-ode.org/ontologies/galen#LoopOfHenle GALEN LOOM
http://purl.obolibrary.org/obo/OMIT_0009221 OMIT LOOM
http://purl.bioontology.org/ontology/MESH/D008138 MESH LOOM
http://purl.obolibrary.org/obo/VHOG_0001270 VHOG LOOM
http://purl.obolibrary.org/obo/MA_0001675 MA LOOM
http://radlex.org/RID/RID31776 RADLEX LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0023986 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008138 RH-MESH LOOM
http://purl.org/sig/ont/fma/fma17698 FMA LOOM
http://purl.jp/bio/4/id/200906029262003110 IOBC LOOM
http://purl.org/obo/owlapi/fma#FMA_17698 BIOMODELS LOOM
http://purl.obolibrary.org/obo/UBERON_0001288 CL LOOM
http://purl.obolibrary.org/obo/UBERON_0001288 EFO LOOM
http://purl.obolibrary.org/obo/UBERON_0001288 HHEAR LOOM
http://purl.obolibrary.org/obo/UBERON_0001288 OBA LOOM
http://purl.obolibrary.org/obo/UBERON_0001288 NIFSTD LOOM
http://purl.obolibrary.org/obo/UBERON_0001288 KTAO LOOM
http://purl.obolibrary.org/obo/UBERON_0001288 GO-PLUS LOOM
http://purl.obolibrary.org/obo/UBERON_0001288 FNS-H LOOM
http://www.projecthalo.com/aura#Loop-Of-Henle AURA LOOM