loading...| Preferred Name |
mucosa of stomach |
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| Synonyms |
ventriculus mucous membrane stomach mucosa stomach mucous membrane organ mucosa of ventriculus stomach organ mucosa mucous membrane of ventriculus mucous membrane of stomach gastric mucous membrane gastric mucosa stomach mucosa of organ ventriculus mucosa of organ tunica mucosa (gaster) ventriculus mucosa organ mucosa of stomach tunica mucosa gastricae ventriculus organ mucosa mucosa of organ of ventriculus mucosa of ventriculus mucosa of organ of stomach tunica mucosa gastris Magenschleimhaut |
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| Definitions |
The mucosal layer that lines the stomach. |
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| ID |
http://purl.obolibrary.org/obo/UBERON_0001199 |
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| capable of | ||
| contributes to morphology of | ||
| database_cross_reference |
galen:GastricMucosa UMLS:C0017136 CALOHA:TS-0404 MESH:D005753 EMAPA:35817 Wikipedia:Gastric_mucosa OpenCyc:Mx8NhB4rvcD6KJwpEbGdrcN5Y29ycB4rvmKNOpwpEbGdrcN5Y29ycB4rvVj5FpwpEbGdrcN5Y29ycB4rvVjlqpwpEbGdrcN5Y29ycA BTO:0001308 SCTID:362131005 NCIT:C32656 FMA:14907 GAID:321 MA:0002683 |
|
| definition |
The mucosal layer that lines the stomach. |
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| depicted_by |
https://upload.wikimedia.org/wikipedia/commons/1/1c/Normal_gastric_mucosa_intermed_mag.jpg |
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| depiction |
https://upload.wikimedia.org/wikipedia/commons/1/1c/Normal_gastric_mucosa_intermed_mag.jpg |
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| has exact synonym |
ventriculus mucous membrane stomach mucosa stomach mucous membrane organ mucosa of ventriculus stomach organ mucosa mucous membrane of ventriculus mucous membrane of stomach gastric mucous membrane gastric mucosa stomach mucosa of organ ventriculus mucosa of organ tunica mucosa (gaster) ventriculus mucosa organ mucosa of stomach tunica mucosa gastricae ventriculus organ mucosa mucosa of organ of ventriculus mucosa of ventriculus mucosa of organ of stomach |
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| has related synonym |
tunica mucosa gastris Magenschleimhaut |
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| has_obo_namespace |
uberon |
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| id |
UBERON:0001199 |
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| in_subset | ||
| label |
mucosa of stomach |
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| notation |
UBERON:0001199 |
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| part_of | ||
| prefixIRI |
UBERON:0001199 |
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| prefLabel |
mucosa of stomach |
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| treeView | ||
| UBPROP_0000001 |
The gastric mucosa is the mucous membrane layer of the stomach which contains the glands and the gastric pits. In men it is about 1 mm thick and its surface is smooth, soft, and velvety. It consists of epithelium, lamina propria, and the muscularis mucosae. In its fresh state, it is of a pinkish tinge at the pyloric end and of a red or reddish-brown color over the rest of its surface. In infancy it is of a brighter hue, the vascular redness being more marked. It is thin at the cardiac extremity, but thicker toward the pylorus. During the contracted state of the organ it is thrown into numerous plaits or rugae, which, for the most part, have a longitudinal direction, and are most marked toward the pyloric end of the stomach, and along the greater curvature. These folds are entirely obliterated when the organ becomes distended. When examined with a lens, the inner surface of the mucous membrane presents a peculiar honeycomb appearance from being covered with funnel-like depressions or foveolae of a polygonal or hexagonal form, which vary from 0.12 to 0.25 mm. in diameter. These are the ducts of the gastric glands, and at the bottom of each may be seen one or more minute orifices, the openings of the gland tubes. Gastric glands are simple or branched tubular glands that emerge on the deeper part of the gastric foveola, inside the gastric areas and outlined by the folds of the mucosa. There are three types of glands: cardiac glands (in the proximal part of the stomach), oxyntic glands (the dominating type of gland), and pyloric glands. The cardiac glands mainly contain mucus producing cells. The bottom part of the oxyntic glands is dominated by zymogen (chief) cells that produce pepsinogen (an inactive precursor of the pepsin enzyme). Parietal cells, which secrete hydrochloric acid are scattered in the glands, with most of them in the middle part. The upper part of the glands consist of mucous neck cells; in this part the dividing cells are seen. The pyloric glands contain mucus-secreting cells. Several types of endocrine cells are found in all regions of the gastric mucosa. In the pyloric glands contain gastrin producing cells (G cells); this hormone stimulates acid production from the parietal cells. ECL (enterochromaffine-like) cells, found in the oxyntic glands release histamine, which also is a powerful stimulant of the acid secretion. The A cells produce glucagon, which mobilizes the hepatic glycogen, and the enterochromaffin cells that produce serotonin, which stimulates the contraction of the smooth muscles. The surface of the mucous membrane is covered by a single layer of columnar epithelium . This epithelium commences very abruptly at the cardiac orifice, where there is a sudden transition from the stratified epithelium of the esophagus. The epithelial lining of the gland ducts is of the same character and is continuous with the general lining of the stomach. [WP,unvetted][Wikipedia:Gastric_mucosa]. |
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| subClassOf |