Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

professional antigen presenting cell

Synonyms

APC

Definitions

Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as constimulatory molecules, and thus can initiate immune responses via T cells. A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.

ID

http://purl.obolibrary.org/obo/ZFA_0009088

comment

Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as constimulatory molecules, and thus can initiate immune responses via T cells.

database_cross_reference

TAO:0009088

CL:0000145

definition

A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.

has exact synonym

APC

has_obo_namespace

zebrafish_anatomy

IAO_0000589

professional antigen presenting cell (zebrafish)

id

ZFA:0009088

in_subset

http://purl.obolibrary.org/obo/zfa#cell_slim

label

professional antigen presenting cell

notation

ZFA:0009088

prefixIRI

ZFA:0009088

prefLabel

professional antigen presenting cell

subClassOf

http://purl.obolibrary.org/obo/CL_0000145

http://purl.obolibrary.org/obo/ZFA_0009309

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