Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

Rubral tremor

Synonyms

Holmes' tremor

Definitions

Rubral tremor can be observed with midbrain injury and probably results from combined lesions of the superior cerebellar peduncle, substantia nigra, and red nucleus with interruption of the outflow pathway from the cerebellum to the motor thalamus. This tremor is present at rest but tends to be slower (3 to 5 Hz) than typical Parkinson tremor (5 to 7 Hz). It also persists unchanged or even increases with postural changes or goal-directed activity. Rubral tremor is characterized by a slow coarse tremor at rest that is exacerbated by postural adjustments and by guided voluntary movements.

ID

http://purl.obolibrary.org/obo/HP_0030665

comment

Rubral tremor can be observed with midbrain injury and probably results from combined lesions of the superior cerebellar peduncle, substantia nigra, and red nucleus with interruption of the outflow pathway from the cerebellum to the motor thalamus. This tremor is present at rest but tends to be slower (3 to 5 Hz) than typical Parkinson tremor (5 to 7 Hz). It also persists unchanged or even increases with postural changes or goal-directed activity.

creator

https://orcid.org/0000-0002-0003-6754

database_cross_reference

MSH:D001259

UMLS:C0750940

definition

Rubral tremor is characterized by a slow coarse tremor at rest that is exacerbated by postural adjustments and by guided voluntary movements.

has exact synonym

Holmes' tremor

label

Rubral tremor

prefixIRI

HP:0030665

prefLabel

Rubral tremor

subClassOf

http://purl.obolibrary.org/obo/HP_0001337

http://purl.obolibrary.org/obo/MP_0000745

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