Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

Abnormality of the intrinsic pathway

Synonyms
Definitions

An abnormality of the intrinsic pathway (also known as the contact activation pathway) of the coagulation cascade. The intrinsic pathway requires coagulation factors VIII, IX, X, XI, and XII, as well as the proteins prekallikrein (PK) and high-molecular-weight kininogen (HK or HMWK), in addition to calcium ions and phospholipids secreted from platelets.

ID

http://purl.obolibrary.org/obo/HP_0010989

comment

The intrinsic pathway requires coagulation factors VIII, IX, X, XI, and XII, as well as the proteins prekallikrein (PK) and high-molecular-weight kininogen (HK or HMWK), in addition to calcium ions and phospholipids secreted from platelets.

creation date

2011-02-08T04:26:55Z

creator

https://orcid.org/0000-0002-0736-9199

database_cross_reference

UMLS:C4023610

definition

An abnormality of the intrinsic pathway (also known as the contact activation pathway) of the coagulation cascade.

id

HP:0010989

label

Abnormality of the intrinsic pathway

notation

HP:0010989

prefLabel

Abnormality of the intrinsic pathway

subClassOf

http://purl.obolibrary.org/obo/HP_0003256

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