Uber Anatomy Ontology

Last uploaded: November 13, 2019
Preferred Name

tympanic membrane

Synonyms

myrinx

membranous wall of tympanic cavity

tympanum

eardrum

paries membranaceus cavi tympani

ear drum

lateral wall of tympanic cavity

Rivinus' membrane

Definitions

A thin membrane that separates the external ear from the middle ear, consisting of two epithelia (one part of the the external accoustic meatus epithelium, the other part of the tympanic cavity epithelium) with a fibrous layer between them. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation of the eardrum can lead to conductive hearing loss. [WP,unvetted].

ID

http://purl.obolibrary.org/obo/UBERON_0002364

adjacent to

http://purl.obolibrary.org/obo/UBERON_0004114

contributes to morphology of

http://purl.obolibrary.org/obo/UBERON_0001756

database_cross_reference

MA:0000257

VHOG:0001146

EV:0100358

FMA:9595

GAID:870

XAO:0000212

MESH:A09.246.397.873

EMAPA:19062

NCIT:C12502

UMLS:C0041445

http://www.snomedbrowser.com/Codes/Details/181180005

http://linkedlifedata.com/resource/umls/id/C0041445

http://en.wikipedia.org/wiki/Tympanic_membrane

definition

A thin membrane that separates the external ear from the middle ear, consisting of two epithelia (one part of the the external accoustic meatus epithelium, the other part of the tympanic cavity epithelium) with a fibrous layer between them. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation of the eardrum can lead to conductive hearing loss. [WP,unvetted].

development_notes

The tympanic membrane (TM) has three layers, two epithelia provided by the external acoustic meatus (EAM) and the MEC, derived respectively from the first pharyngeal cleft and pouch, and a mesenchymally derived fibrous stratum

develops_from

http://purl.obolibrary.org/obo/UBERON_0009213

external_definition

The thin membrane which closes externally the cavity of the middle ear and is deeply sited at the bottom of the external auditory meatus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]

external_ontology_notes

most AOs consider this part of the middle ear, so we go with this and place it in the middle ear as a border to the external, although it could be considered to overlap the external ear in that it has an EAM layer as part - for this reason we do not consider middle and external ear to be spatially disjoint.

has_exact_synonym

myrinx

membranous wall of tympanic cavity

eardrum

paries membranaceus cavi tympani

ear drum

lateral wall of tympanic cavity

Rivinus' membrane

has_obo_namespace

uberon

has_related_synonym

tympanum

homology_notes

In particular, a tympanic membrane was not present in the earliest tetrapods (...). An ear utilizing a tympanic membrane evolved independently at least three times in tetrapods: (1) in the lineage that leads to anurans (frogs), (2) in the line of evolution to turtles and diapsids, and (3) in the late synapsid lineage that gave rise to mammals.[well established][VHOG]

id

UBERON:0002364

in_subset

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

http://purl.obolibrary.org/obo/uberon/core#organ_slim

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

label

tympanic membrane

notation

UBERON:0002364

part_of

http://purl.obolibrary.org/obo/UBERON_0001756

prefixIRI

UBERON:0002364

prefLabel

tympanic membrane

treeView

http://purl.obolibrary.org/obo/UBERON_0009213

http://purl.obolibrary.org/obo/UBERON_0001756

has_part

http://purl.obolibrary.org/obo/UBERON_0010069

http://purl.obolibrary.org/obo/UBERON_0010070

http://purl.obolibrary.org/obo/UBERON_0005042

subClassOf

http://purl.obolibrary.org/obo/UBERON_0010314

http://purl.obolibrary.org/obo/UBERON_0000094

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/MA_0000257 MA LOOM
http://purl.obolibrary.org/obo/VHOG_0001146 VHOG LOOM
http://purl.jp/bio/4/id/200906037455442262 IOBC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12502 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12502 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12502 NCIT LOOM
http://www.projecthalo.com/aura#Tympanic-Membrane AURA LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 GO-PLUS LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 CCONT LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 CCONT SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 EFO LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 EFO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 ENVO LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 ENVO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 GO-PLUS LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 UPHENO LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 UPHENO SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 NIFSTD LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 CL LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 CL SAME_URI
http://purl.obolibrary.org/obo/UBERON_0002364 OBA LOOM
http://purl.obolibrary.org/obo/UBERON_0002364 OBA SAME_URI
http://purl.jp/bio/11/meo/MEO_0000800 MEO LOOM
http://purl.bioontology.org/ontology/MESH/D014432 MESH LOOM
http://purl.bioontology.org/ontology/LNC/LA9368-7 LOINC LOOM
http://purl.bioontology.org/ontology/RCD/7N173 RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A09.246.272.702 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU014731 LOINC LOOM
http://purl.org/sig/ont/fma/fma9595 FMA LOOM
http://purl.org/obo/owlapi/fma#FMA_9595 BIOMODELS LOOM
http://purl.obolibrary.org/obo/EMAPA_19062 EMAPA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014432 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Tympanic_Membrane CSEO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Tympanic_Membrane SYN LOOM
http://radlex.org/RID/RID10100 RADLEX LOOM
http://purl.bioontology.org/ontology/LNC/LP7665-5 LOINC LOOM