loading...| Preferred Name |
zona incerta |
|
| Synonyms |
nucleus of the zona incerta zona incerta proper |
|
| Definitions |
The zona incerta is a horizontally elongated region of gray matter cells in the subthalamus below the thalamus. Its connections project extensively over the brain from the cerebral cortex down into the spinal cord. Its function is unknown though several have been proposed related to 'limbic-motor integration' such as controlling visceral activity and pain; gating sensory input and synchronizing cortical and subcortical brain rhythms. Its dysfunction may play a role in central pain syndrome. It is also been identified as a promising deep brain stimulation therapy target for treating Parkinsons Disease. Its existence was first described by Auguste Forel in 1877 as a 'region of which nothing certain can be said'. A hundred and thirty years later in 2007, Nadia Urbain and Martin Deschênes of Université Laval noted that the 'zona incerta is among the least studied regions of the brain; its name does not even appear in the index of many textbooks. ' [WP,unvetted]. |
|
| ID |
http://purl.obolibrary.org/obo/UBERON_0001907 |
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| database_cross_reference |
neuronames:438 BTO:0003146 BM:Die-VTh-ZI MESH:D065820 SCTID:369186007 EMAPA:35930 Wikipedia:Zona_incerta BAMS:ZI DHBA:10463 FMA:62038 HBA:4507 MA:0000878 MBA:797 |
|
| definition |
The zona incerta is a horizontally elongated region of gray matter cells in the subthalamus below the thalamus. Its connections project extensively over the brain from the cerebral cortex down into the spinal cord. Its function is unknown though several have been proposed related to 'limbic-motor integration' such as controlling visceral activity and pain; gating sensory input and synchronizing cortical and subcortical brain rhythms. Its dysfunction may play a role in central pain syndrome. It is also been identified as a promising deep brain stimulation therapy target for treating Parkinsons Disease. Its existence was first described by Auguste Forel in 1877 as a 'region of which nothing certain can be said'. A hundred and thirty years later in 2007, Nadia Urbain and Martin Deschênes of Université Laval noted that the 'zona incerta is among the least studied regions of the brain; its name does not even appear in the index of many textbooks. ' [WP,unvetted]. |
|
| has_obo_namespace |
uberon |
|
| has_related_synonym |
nucleus of the zona incerta zona incerta proper |
|
| id |
UBERON:0001907 |
|
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas |
|
| label |
zona incerta |
|
| notation |
UBERON:0001907 |
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| part_of | ||
| prefLabel |
zona incerta |
|
| present_in_taxon | ||
| treeView | ||
| mutually_spatially_disjoint_with |
http://purl.obolibrary.org/obo/UBERON_0001931 http://purl.obolibrary.org/obo/UBERON_0001933 |
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| subClassOf |