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Uber Anatomy Ontology
Last uploaded:
January 15, 2025
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Id | http://purl.obolibrary.org/obo/UBERON_0000956
http://purl.obolibrary.org/obo/UBERON_0000956
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Preferred Name | cerebral cortex |
Definitions |
The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex.
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Synonyms | |
Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | |
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label |
cerebral cortex
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prefLabel |
cerebral cortex
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database_cross_reference |
BAMS:Cerebral_cortex
neuronames:39
BIRNLEX:1494
MAT:0000108
PBA:128011354
EMAPA:17544
EHDAA2:0000234
SCTID:362880003
NCIT:C12443
BTO:0000233
MIAA:0000108
UMLS:C0007776
MESH:D002540
CALOHA:TS-0091
Wikipedia:Cerebral_cortex
EFO:0000328
VHOG:0000722
BAMS:C
BAMS:CTX
BAMS:Cx
BM:Tel-Cx
DHBA:10159
EHDAA:5464
EV:0100166
FMA:61830
GAID:629
HBA:4008
MA:0000185
MBA:688
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notation |
UBERON:0000956
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in_subset |
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has_related_synonym |
cortical plate (areas)
pallium of the brain
cortical plate (CTXpl)
cortex cerebri
brain cortex
cortex cerebralis
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has developmental contribution from | |
id |
UBERON:0000956
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has_obo_namespace |
uberon
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part_of | |
curator note |
We follow NIFSTD in defining cerebral cortex and including both neocortex and hippocampal formation (DG+hippocampus).
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depiction | |
taxon_notes |
hagfishes have independently evolved a highly laminated cerebral cortex, comparable in many ways to the cerebral cortex of mammals [http://icb.oxfordjournals.org/content/42/4/743]
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external_definition |
The cerebral cortex is a structure within the brain that plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It constitutes the outermost layer of the cerebrum. In preserved brains, it has a grey color, hence the name 'grey matter'. Grey matter is formed by neurons and their unmyelinated fibers, whereas the white matter below the grey matter of the cortex is formed predominantly by myelinated axons interconnecting different regions of the central nervous system. The human cerebral cortex is 2-4 mm (0.08-0.16 inches) thick. The surface of the cerebral cortex is folded in large mammals, such that more than two-thirds of the cortical surface is buried in the grooves, called 'sulci. ' The phylogenetically most recent part of the cerebral cortex, the neocortex, also called isocortex, is differentiated into six horizontal layers; the more ancient part of the cerebral cortex, the hippocampus (also called archicortex), has at most three cellular layers, and is divided into subfields. Relative variations in thickness or cell type (among other parameters) allow us to distinguish between different neocortical architectonic fields. The geometry of at least some of these fields seems to be related to the anatomy of the cortical folds, and, for example, layers in the upper part of the cortical ridges seem to be more clearly differentiated than in its deeper parts. [WP,unvetted][Wikipedia:Cerebral_cortex].
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homology_notes |
Migration of neurons from the basal or striatal portions of the anterior part of the neural tube occurs to varying degrees in different vertebrate classes, but a true cerebral cortex is generally acknowledged to have made its first appearance in reptiles. The definition can be unambiguous, since 'cortex' simply implies the existence of a surface neuronal layer with an overlying 'zonal lamina' or 'molecular' layer containing dendrites and axons, which is separated from the underlying basal 'matrix' by white matter. Although reptilian cerebral cortex does indeed fulfill these conditions in certain locations, the separation from striatal structures is often indistinct, so that it may even be argued that some primitive dipnoans possess a pallium or cortex. Nevertheless, an extensive laminated layer separated by underlying white matter is well represented only in reptiles and mammals.[well established][VHOG]
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functionally related to | |
present in taxon | |
capable of part of | |
subClassOf | |
overlaps | |
type | |
has_exact_synonym |
cortex of cerebral hemisphere
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contributes to morphology of | |
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