loading...| Preferred Name |
cholestasis [toxic course] |
|
| Synonyms |
|
|
| Definitions |
This entity is under construction. Drug induced liver injury (DILI) is categorized as drug induced cholestasis (DIC), drug-induced hepatitis, and is mixed liver injury. Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS). phallodin, microsystin, amantin is facilitated by the uptake thpugh OATPs. rifampicin, bosentan, troglitazone directly inhibit BSEP. The totality of all processes through which cholestasis is realized. |
|
| ID |
http://purl.obolibrary.org/obo/TXPO_0001277 |
|
| comment |
This entity is under construction. Drug induced liver injury (DILI) is categorized as drug induced cholestasis (DIC), drug-induced hepatitis, and is mixed liver injury. Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS). phallodin, microsystin, amantin is facilitated by the uptake thpugh OATPs. rifampicin, bosentan, troglitazone directly inhibit BSEP. |
|
| description |
BSEP inhibition : bosentan, cyclosporin, glibenclamide, rifampicin, rifamycin |
|
| database_cross_reference |
http://purl.bioontology.org/ontology/MESH/D002779 |
|
| definition |
The totality of all processes through which cholestasis is realized. |
|
| has core process | ||
| has part | ||
| label |
cholestasis [toxic course] |
|
| prefixIRI |
TXPO:0001277 |
|
| prefLabel |
cholestasis [toxic course] |
|
| subClassOf |