Toxic Process Ontology

Last uploaded: December 6, 2022
Preferred Name

cellular damage

Synonyms

cell and tissue damage

Definitions

Cellular damage is a subtype of damaging: A process that injuries the structure of the cell as the direct or indirect result of an external force.

ID

http://purl.obolibrary.org/obo/TXPO_0000225

database_cross_reference

http://purl.jp/bio/4/id/200906069918862451

PMID:8703628

https://en.wikipedia.org/wiki/Cell_damage

Cell damage (also known as cell injury) is a variety or changes of stress that a cell suffers due to external as well internal environmental changes. Among other causes, this can be due to physical, chemical, infectious, biological, nutritional or immunological factors. Cell damage can be reversible or irreversible. Depending on the extent of injury, the cellular response may be adaptive and where possible, homeostasis is restored. Cell death occurs when the severity of the injury exceeds the cell’s ability to repair itself. Cell death is relative to both the length of exposure to a harmful stimulus and the severity of the damage caused. Cell death may occur by necrosis or apoptosis.

definition

Cellular damage is a subtype of damaging: A process that injuries the structure of the cell as the direct or indirect result of an external force.

hasBroadSynonym

cell and tissue damage

label

cellular damage

prefixIRI

TXPO:0000225

prefLabel

cellular damage

subClassOf

http://purl.obolibrary.org/obo/TXPO_0000222

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