Toxic Process Ontology

Last uploaded: December 6, 2022
Preferred Name

pemoline
Synonyms

Myamin

Dantromin

Hyton

2-Amino-5-phenyl-4(5H)-oxazolone

Betanamin

pemolinum

Nitan

phenylpseudohydantoin

5-phenyl-2-imino-4-oxooxazolidine

5-phenylisohydantion

Deltamine

pheniminooxazolidinone

5-phenyl-2-imino-4-oxazolidinone

2-imino-4-keto-5-phenyltetrahydrooxazole

2-imino-5-phenyl-4-oxazolidinone

Cylert

pemoline

Azoxodon

Notair

phenylisohydantoin

pemolina

2-amino-5-phenyl-1,3-oxazol-4(5H)-one

Definitions

A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.

ID

http://purl.obolibrary.org/obo/CHEBI_7953

database_cross_reference

PMID:641739

LINCS:LSM-5159

Drug_Central:2075

PMID:772696

PMID:2210262

PMID:4021028

PMID:11216184

PMID:2388127

PMID:2303976

CAS:2152-34-3

DrugBank:DB01230

Reaxys:151559

definition

A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.

has role

http://purl.obolibrary.org/obo/CHEBI_35337

has_exact_synonym

2-amino-5-phenyl-1,3-oxazol-4(5H)-one

has_related_synonym

Myamin

Dantromin

Hyton

2-Amino-5-phenyl-4(5H)-oxazolone

Betanamin

pemolinum

Nitan

phenylpseudohydantoin

5-phenyl-2-imino-4-oxooxazolidine

5-phenylisohydantion

Deltamine

pheniminooxazolidinone

5-phenyl-2-imino-4-oxazolidinone

2-imino-4-keto-5-phenyltetrahydrooxazole

2-imino-5-phenyl-4-oxazolidinone

Cylert

pemoline

Azoxodon

Notair

phenylisohydantoin

pemolina

id

CHEBI:7953

label

pemoline

notation

CHEBI:7953

prefLabel

pemoline

subClassOf

http://purl.obolibrary.org/obo/CHEBI_50860

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_7953 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7953 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7953 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7953 HOIP SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7953 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_7953 CHEBI SAME_URI
http://www.co-ode.org/ontologies/galen#Pemoline GALEN LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147031 NDFRT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47655 NCIT LOOM
http://purl.bioontology.org/ontology/SNMI/C-65530 SNMI LOOM
http://purl.bioontology.org/ontology/RXNORM/7966 RXNORM LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Pemoline APAONTO LOOM
http://purl.bioontology.org/ontology/ATC/N06BA05 ATC LOOM
http://purl.jp/bio/4/id/200906056215641920 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9407 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/MTHU015176 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.129.462.673 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018209 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/OMIT_0011383 OMIT LOOM
http://scai.fraunhofer.de/MSOntology#Pemoline MSO LOOM
http://purl.bioontology.org/ontology/MESH/D010389 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387393000 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4018726 VANDF LOOM
http://purl.obolibrary.org/obo/dinto_DB01230 DINTO LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Pemoline STMSO LOOM
http://purl.bioontology.org/ontology/LNC/LP16236-9 LOINC LOOM
http://purl.bioontology.org/ontology/RCD/db1.. RCD LOOM
https://go.drugbank.com/drugs/DB01230 MDM LOOM
http://purl.obolibrary.org/obo/MESH_D010389 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010389 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0030800 OCHV LOOM
http://purl.bioontology.org/ontology/NDDF/001384 NDDF LOOM
http://purl.obolibrary.org/obo/NCIT_C47655 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_7953 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_7953 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_7953 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_7953 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_7953 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_7953 CHEBI LOOM