Toxic Process Ontology

Last uploaded: December 6, 2022
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Preferred Name

dacarbazine
Synonyms

Dtic-Dome (TN)

NSC-45388

4-(dimethyltriazeno)imidazole-5-carboxamide

DIC

dacarbazinum

4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide

5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide

HSDB 3219

5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide

deticene

dacarbazina

5-(dimethyltriazeno)imidazole-4-carboxamide

5-(3,3-dimethyltriazeno)imidazole-4-carboxamide

ICDMT

dacarbazine

4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide

NCI-C04717

Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)-

NSC 45388

DTIC

Di-me-triazenoimidazolecarboxamide

5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
Definitions

A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma.
ID

http://purl.obolibrary.org/obo/CHEBI_4305
database_cross_reference

PMID:29287706

CAS:4342-03-4

PMID:10751609

PMID:28419676

PMID:29184162

PMID:20082117

PMID:12195827

DrugBank:DB00851

PMID:28250333

PMID:21471822

PMID:28387914

PMID:29305638

Drug_Central:773

PMID:11318431

PMID:29344241

Reaxys:521487

PMID:29076951

PMID:23029050

PMID:28096700

PMID:29296081

PMID:21654834

PMID:15010317

PMID:23318786

PMID:26940170

Beilstein:521487
definition

A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma.
has role

http://purl.obolibrary.org/obo/CHEBI_35610

http://purl.obolibrary.org/obo/CHEBI_22333

http://purl.obolibrary.org/obo/CHEBI_50903

http://purl.obolibrary.org/obo/CHEBI_50266
has_exact_synonym

5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
has_related_synonym

Dtic-Dome (TN)

NSC-45388

4-(dimethyltriazeno)imidazole-5-carboxamide

DIC

dacarbazinum

4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide

5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide

HSDB 3219

5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide

deticene

dacarbazina

5-(dimethyltriazeno)imidazole-4-carboxamide

5-(3,3-dimethyltriazeno)imidazole-4-carboxamide

ICDMT

dacarbazine

4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide

NCI-C04717

Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)-

NSC 45388

DTIC

Di-me-triazenoimidazolecarboxamide
id

CHEBI:4305
label

dacarbazine
notation

CHEBI:4305
prefLabel

dacarbazine
subClassOf

http://purl.obolibrary.org/obo/CHEBI_50860
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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_4305 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4305 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4305 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4305 HOIP SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4305 DINTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4305 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4305 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4305 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4305 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_4305 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/NCIT_C411 BERO LOOM
http://purl.obolibrary.org/obo/MESH_D003606 BERO LOOM
http://purl.bioontology.org/ontology/MESH/D003606 MESH LOOM
http://purl.jp/bio/4/id/200906004842005622 IOBC LOOM
http://purl.bioontology.org/ontology/SNMI/C-78090 SNMI LOOM
http://stirdf.jst.go.jp/id/200907031160358150 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3597 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4305 NIFSTD LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017542 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/VANDF/4018386 VANDF LOOM
http://www.co-ode.org/ontologies/galen#Dacarbazine GALEN LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039768 PDQ LOOM
http://www.drugbank.ca/drugs/DB00851 FTC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.925.200 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387441003 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003606 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/h54.. RCD LOOM
http://purl.bioontology.org/ontology/RXNORM/3098 RXNORM LOOM
http://purl.bioontology.org/ontology/CSP/1548-5525 CRISP LOOM
http://purl.bioontology.org/ontology/NDDF/002671 NDDF LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C411 NCIT LOOM
https://go.drugbank.com/drugs/DB00851 MDM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146713 NDFRT LOOM
http://purl.bioontology.org/ontology/ATC/L01AX04 ATC LOOM
http://purl.obolibrary.org/obo/OMIT_0004890 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.129.308.240 RH-MESH LOOM