loading...| Preferred Name | zileuton | |
| Synonyms |
N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea Leutrol Zyflo N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea zileutonum zileuton 1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea Zileuton |
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| Definitions |
A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_10112 |
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| database_cross_reference |
CAS:111406-87-2 LINCS:LSM-5084 DrugBank:DB00744 PMID:20204486 PMID:19645854 Drug_Central:2862 PMID:19309543 PMID:20436887 |
|
| definition |
A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma. |
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| has role |
http://purl.obolibrary.org/obo/CHEBI_64964 http://purl.obolibrary.org/obo/CHEBI_49159 |
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| has_exact_synonym |
1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea Zileuton |
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| has_related_synonym |
N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea Leutrol Zyflo N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea zileutonum zileuton |
|
| id |
CHEBI:10112 |
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| label |
zileuton |
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| notation |
CHEBI:10112 |
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| prefLabel |
zileuton |
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| subClassOf |