loading...| Preferred Name | Transforming growth factor beta | |
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| ID |
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_f41ef157_9218_4637_a1be_a98c0b250174 |
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A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins. |
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Transforming growth factor beta |
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| prefixIRI |
OWLClass_f41ef157_9218_4637_a1be_a98c0b250174 |
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Transforming growth factor beta |
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| synonyms |
TGF-b TGFbeta |
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| subClassOf |
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_ed013536_d323_4787_9e6d_25c43b834431 |