The Stroke Ontology

Last uploaded: August 7, 2018
Preferred Name

Monoclonal antibodies

Synonyms
ID

http://www.semanticweb.org/ontologies/STO.owl#OWLClass_1ac7b0ee_1163_4f11_ad81_cb5da045c27c

isDefinedBy

Monoclonal antibodies can block an intercellular adhesion molecule (ICAM) on the endothelium to prevent adhesion of white blood cells to the vessel wall. Because anti-ICAM antibodies appear to block an early step in reperfusion-related injury, they present a hopeful mechanism for preserving neuronal function.

label

Monoclonal antibodies

prefixIRI

OWLClass_1ac7b0ee_1163_4f11_ad81_cb5da045c27c

prefLabel

Monoclonal antibodies

references

Clark WM, Madden KP, Rothlein R, Zivin JA. Reduction of central nervous system ischemic injury by monoclonal antibody to intercellular adhesion molecule. J Neurosurg. 1991 Oct. 75(4):623-7

source

http://emedicine.medscape.com/article/1161422-overview#a3

synonyms

murine intercellular adhesion molecule-1 antibody

Anti-ICAM-1 monoclonal antibody R6.5

murine ICAM-1 antibody

subClassOf

http://www.semanticweb.org/ontologies/STO.owl#OWLClass_9cfa147d_3e91_4ff0_bf88_b949f7f17770

Delete Subject Author Type Created
No notes to display