The Stroke Ontology

Last uploaded: August 7, 2018
Preferred Name

Neurochemical changes
Synonyms
ID

http://www.semanticweb.org/ontologies/STO.owl#OWLClass_1403b132_6069_4352_b80e_f4c83cab5190

isDefinedBy

Postmortem (by immunohistochemical staining techniques) and in vivo (by microdialysis) evaluation of neurochemical changes following stroke in animal models showed that while aspartate, glutamate, inosine, hypoxanthine, adenosine and γ-aminobutyrate increases in the acute ischemic period, glycine seems to increase with prolonged ischemia and some neuroactive substances increase in peri-infarct region (such as tyrosine hydroxylase, neuropeptide Y), and some (neuropeptide Y, leuleuenkephalin, neurotensin, and dynorphin) in nuclei of amygdala which are not infarcted.

label

Neurochemical changes

prefixIRI

OWLClass_1403b132_6069_4352_b80e_f4c83cab5190

prefLabel

Neurochemical changes

references

Durukan, A., & Tatlisumak, T. (2007). Acute ischemic stroke: overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia. Pharmacology Biochemistry and Behavior, 87(1), 179-197.

subClassOf

http://www.semanticweb.org/ontologies/STO.owl#OWLClass_23e71a33_674f_4315_a558_53eb2597b5d2

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