SNOMED CT, US Edition

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/SNOMEDCT/1367656002
http://purl.bioontology.org/ontology/SNOMEDCT/1367656002
Preferred Name

SLC12A2-related developmental delay, intellectual disability, sensorineural deafness syndrome

Definitions
A rare genetic, syndromic intellectual disability syndrome characterized by mild to severe global developmental delay and intellectual disability, delayed or absent speech and walking, and bilateral sensorineural deafness. Severity of the symptoms are variable. Patients may manifest with profound hypotonia, severe feeding difficulties and secretory dysfunction. Autistic features, spasticity, mild and non-specific dysmorphic features and cardiac defects were reported in some patients. A rare genetic, syndromic intellectual disability syndrome characterised by mild to severe global developmental delay and intellectual disability, delayed or absent speech and walking, and bilateral sensorineural deafness. Severity of the symptoms are variable. Patients may manifest with profound hypotonia, severe feeding difficulties and secretory dysfunction. Autistic features, spasticity, mild and non-specific dysmorphic features and cardiac defects were reported in some patients.
Synonyms
Solute carrier family 12 member 2-related developmental delay, intellectual disability, sensorineural deafness syndrome (disorder)
Solute carrier family 12 member 2-related developmental delay, intellectual disability, sensorineural deafness syndrome
Type http://www.w3.org/2002/07/owl#Class
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