SNOMED CT, US Edition

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/SNOMEDCT/1237343009
http://purl.bioontology.org/ontology/SNOMEDCT/1237343009
Preferred Name

Otodental syndrome

Definitions
A very rare inherited condition with characteristics of grossly enlarged canine and molar teeth (globodontia) associated with bilateral sensorineural high-frequency hearing deficit with an age of onset that varies from early childhood to middle age. Variable facial dysmorphism has also been reported. Haploinsufficiency in the fibroblast growth factor 3 (FGF3) gene (11q13) has been reported in patients with otodental syndrome and is thought to cause the phenotype. The condition appears to be inherited in an autosomal dominant manner with complete to variable penetrance and variable expressivity. Otodental syndrome is a very rare inherited condition characterised by grossly enlarged canine and molar teeth (globodontia) associated with sensorineural hearing loss. Otodental syndrome is a very rare inherited condition characterized by grossly enlarged canine and molar teeth (globodontia) associated with sensorineural hearing loss.
Synonyms
Otodental dysplasia
Otodental syndrome (disorder)
Type http://www.w3.org/2002/07/owl#Class
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