Sepsis Ontology

Last uploaded: May 14, 2024
Preferred Name

Troponin I

Synonyms
ID

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Troponin_I

definition

Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. In the absence of calcium, Troponin I binds actin, inhibits actomyosin ATPase activity, and inhibits F-actin-myosin interactions. The troponin I gene family comprises three isoforms: skeletal TNI-fast, skeletal TNI-slow, and TNI-cardiac.

label

Troponin I

prefixIRI

Troponin_I

prefLabel

Troponin I

reference

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17343

Synonyms

TNNI TnI Troponin I

subClassOf

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Cytoskeletal_Protein

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