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Sepsis Ontology
Last uploaded:
May 14, 2024
Acronym | SEPON |
Visibility | Public |
Description | The Sepsis Ontology (SEPON) is a disease-specific ontology that defines the concepts and relationships between concepts in the field of sepsis and related diseases, contributing to data standardization and providing precise and personalized diagnosis, treatment and prognosis recommandations for sepsis. |
Status | Alpha |
Format | OWL |
Language | English |
Contact | ZHANG CHI, zhangchi8359@wchscu.cn |
Categories | Health, Human |
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Id | http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Tinidazole
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Tinidazole
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Preferred Name | Tinidazole |
Type | http://www.w3.org/2002/07/owl#Class |
All Properties
definition | A 5-nitroimidazole derivative with antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized and yields nitrite anions and metronidazole. Metronidazole's nitro group in turn is reduced via the parasite ferredoxin, thereby generating a series of free nitro radicals including nitro anions. Toxicity is achieved via depletion of sulfhydryl groups and DNA strand breaks with multiple hits having an additive effect and ultimately leading to cell death. |
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prefLabel | Tinidazole
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label | Tinidazole
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Synonyms | Fasigyn
Simplotan
TDZ
TINIDAZOLE
Tindamax
Tinidazole
tinidazole
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prefixIRI | Tinidazole
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subClassOf | |
type | |
reference |
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