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Sepsis Ontology
Last uploaded:
May 14, 2024
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| Preferred Name | Lincosamide Antibiotic | |
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| ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Lincosamide_Antibiotic |
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| definition |
Any synthetic or semi-synthetic derivative of lincomycin, first isolated from a soil actinomycete Streptomyces lincolnensis, with antibacterial activity. Lincosamide antibiotics bind to the 23S rRNA in the large 50S subunit of bacterial ribosomes, thereby preventing the peptidyl-tRNA translocation from the A site to the P site. This results in peptidyl-tRNA dissociation from ribosomes, and leads to the release of incomplete proteins, ultimately causing cell death.
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| label |
Lincosamide Antibiotic
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| prefixIRI |
Lincosamide_Antibiotic
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| prefLabel |
Lincosamide Antibiotic
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| reference | ||
| Synonyms |
Lincosamide Antibiotic
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| subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Antibiotic |
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| Mapping To | Ontology | Source |
|---|---|---|
| http://purl.obolibrary.org/obo/ARO_0000017 | ARO | LOOM |
| http://purl.obolibrary.org/obo/ARO_0000017 | ARO | LOOM |
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C82922 | NCIT | LOOM |
| http://purl.obolibrary.org/obo/NCIT_C82922 | BERO | LOOM |