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Sepsis Ontology
Last uploaded:
May 14, 2024
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Preferred Name | Ketoconazole | |
Synonyms |
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ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Ketoconazole |
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definition |
A synthetic derivative of phenylpiperazine with broad antifungal properties and potential antineoplastic activity. Ketoconazole inhibits sterol 14-a-dimethylase, a microsomal cytochrome P450-dependent enzyme, thereby disrupting synthesis of ergosterol, an important component of the fungal cell wall.
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label |
Ketoconazole
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prefixIRI |
Ketoconazole
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prefLabel |
Ketoconazole
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reference | ||
Synonyms |
Ketoconazole
Cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazole-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine
Orifungal M
ketoconazole
KETOCONAZOLE
Fungarest
Fungoral
Ketoderm
Ketoisdin
Nizoral
Panfungol
R-41400
Xolegel
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subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Antifungal_Agent |
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