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Sepsis Ontology
Last uploaded:
May 14, 2024
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| Preferred Name | Fluconazole | |
| Synonyms |
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| ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Fluconazole |
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| definition |
A synthetic triazole with antifungal activity. Fluconazole preferentially inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols, the loss of normal fungal sterols, and fungistatic activity. Mammalian cell demethylation is much less sensitive to fluconazole inhibition.
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| label |
Fluconazole
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| prefixIRI |
Fluconazole
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| prefLabel |
Fluconazole
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| reference | ||
| Synonyms |
fluconazole
Fluconazole
alpha-(2,4-difluorophenyl)-alpha- (1,2,4-triazol-1-ylmethyl)-1,2, 4- triazole-1-ethanol
FLUCONAZOLE
Diflucan
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| subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Antifungal_Agent |
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