loading...| Preferred Name |
Chronic Kidney Disease |
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| Synonyms |
Chronic Kidney Injury Chronic Renal Failure CKD |
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| Definitions |
Evidence of kidney damage includes pathologic abnormalities or markers of kidney damage (i.e., proteinuria) independent of cause. Kidney disease severity is classified into five stages according to the level of GFR and presence of albuminuria. Chronic kidney disease (CKD) is defined as either having a glomerular filtration rate (GFR) of <60 mL/min/1.73 mL for >3 months with or without kidney damage or having evidence of kidney damage for 3 months, with or without decreased GFR. |
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| ID |
http://purl.obolibrary.org/obo/SCDO_0000226 |
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| rdfs:comment |
Evidence of kidney damage includes pathologic abnormalities or markers of kidney damage (i.e., proteinuria) independent of cause. Kidney disease severity is classified into five stages according to the level of GFR and presence of albuminuria. |
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| curator note |
Suggest update to description in DO (currently no definition). |
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| database cross reference |
DOID:784 |
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| dc:creator |
SCDO |
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| dc:source |
NHLBI SCD New guidelines 2014. |
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| definition |
Chronic kidney disease (CKD) is defined as either having a glomerular filtration rate (GFR) of <60 mL/min/1.73 mL for >3 months with or without kidney damage or having evidence of kidney damage for 3 months, with or without decreased GFR. |
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| definition source |
NHLBI SCD New guidelines 2014. |
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| diagnosed using measurement |
http://purl.obolibrary.org/obo/CMO_0000057 http://purl.obolibrary.org/obo/SCDO_0001209 http://purl.obolibrary.org/obo/SCDO_0001212 http://purl.obolibrary.org/obo/SCDO_0001210 |
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| diagnosed using tool |
http://purl.obolibrary.org/obo/SCDO_0001205 |
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| existence in other ontologies |
Few but definitions not specific enough |
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| has age of onset |
When assessed by albuminuria, often presents in second decade of life in sickle cell disease and prevalence increases with age. |
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| has disease stage |
CKD is classified using a combination of GFR and ACR categories |
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| hasExactSynonym |
Chronic Kidney Injury Chronic Renal Failure CKD |
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| in guideline |
http://purl.obolibrary.org/obo/SCDO_1000150 http://purl.obolibrary.org/obo/SCDO_1000152 http://purl.obolibrary.org/obo/SCDO_1000149 |
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| is caused by |
Sickle cell disease, hypertension, diabetes, polycystic kidney disease, glomerulonephritis, various other causes. |
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| is characterised by |
Reduced glomerular filtration, elevated creatinine, anemia, bone disease, uremia. |
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| prefixIRI |
SCDO:0000226 |
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| prefLabel |
Chronic Kidney Disease |
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| rdfs:label |
Chronic Kidney Disease |
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| treated with |
http://purl.obolibrary.org/obo/SCDO_0000067 |
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| subClassOf |