Subcellular Anatomy Ontology

Last uploaded: March 13, 2018
Preferred Name

NMDA Receptor
Synonyms
ID

http://ccdb.ucsd.edu/SAO/1.2#sao794753833

curationStatus

uncurated

definition

A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity (MSH).

label

NMDA Receptor

prefixIRI

sao794753833

prefLabel

NMDA Receptor

sao_ID

sao794753833

umls_ID

C0080093

subClassOf

http://ccdb.ucsd.edu/SAO/1.2#sao1164727693

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