loading...| Preferred Name | Cyclophosphamide | |
| Synonyms |
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| Definitions |
A synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C405 |
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| definition |
A synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death. |
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| isDefinedBy | ||
| label |
Cyclophosphamide |
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| prefixIRI |
ncit:C405 |
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| prefLabel |
Cyclophosphamide |
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| seeAlso |
EuroCAT Umbrella Protocol for NSCLC |
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| subClassOf |