Link to this page
Regulation of Gene Expression Ontolology
| Preferred Name | SAGA complex | |
| Synonyms |
Spt-Ada-Gcn5-acetyltransferase complex |
|
| Definitions |
A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof - additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20|Ada5, which interact with the TATA-binding protein (TBP) - the Ada group, consisting of Ada1, Ada2, Ada3, Ada4|Gcn5, and Ada5|Spt20, which is functionally linked to the nucleosomal HAT activity - Tra1, an ATM|PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters - the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery. |
|
| ID |
http://purl.obolibrary.org/obo/GO_0000124 |
|
| altLabel |
Spt-Ada-Gcn5-acetyltransferase complex
|
|
| definition |
A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof - additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20|Ada5, which interact with the TATA-binding protein (TBP) - the Ada group, consisting of Ada1, Ada2, Ada3, Ada4|Gcn5, and Ada5|Spt20, which is functionally linked to the nucleosomal HAT activity - Tra1, an ATM|PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters - the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery.
|
|
| hasOBONamespace |
cellular_component
|
|
| id |
GO:0000124
|
|
| notation |
GO:0000124
|
|
| prefLabel |
SAGA complex
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |