Regulation of Gene Expression Ontolology

Last uploaded: December 16, 2015
Preferred Name

Paget disease of bone
Synonyms

PDB

Definitions

(PDB) - Metabolic bone disease affecting the axial skeleton and characterized by focal areas of increased and disorganized bone turn-over due to activated osteoclasts. Manifestations of the disease include bone pain, deformity, pathological fractures, deafness, neurological complications and increased risk of osteosarcoma. PDB is a chronic disease affecting 2 to 3% of the population above the age of 40 years. - (PDB2) - Bone- remodeling disorder with clinical similarities to FEO. Unlike FEO, however, affected individuals have involvement of the axial skeleton with lesions in the spine, pelvis and skull.

ID

http://identifiers.org/omim/602080

altLabel

PDB

definition

(PDB) - Metabolic bone disease affecting the axial skeleton and characterized by focal areas of increased and disorganized bone turn-over due to activated osteoclasts. Manifestations of the disease include bone pain, deformity, pathological fractures, deafness, neurological complications and increased risk of osteosarcoma. PDB is a chronic disease affecting 2 to 3% of the population above the age of 40 years. - (PDB2) - Bone- remodeling disorder with clinical similarities to FEO. Unlike FEO, however, affected individuals have involvement of the axial skeleton with lesions in the spine, pelvis and skull.

id

OMIM:602080

notation

OMIM:602080

prefLabel

Paget disease of bone

subClassOf

http://purl.obolibrary.org/obo/OGMS_0000031

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