Regulation of Transcription Ontology

Last uploaded: December 4, 2018
Preferred Name

Glanzmann thrombasthenia
Synonyms

GT

Definitions

(GT) - A common inherited disease of platelet aggregation. It is characterized by mucocutaneous bleeding of mild-to-moderate severity. GT has been classified clinically into types I and II. In type I, platelets show absence of the glycoprotein IIb-IIIa complexes at their surface and lack fibrinogen and clot retraction capability. In type II, the platelets express the GPIIb-IIIa complex at reduced levels, have detectable amounts of fibrinogen, and have low or moderate clot retraction capability.

ID

http://identifiers.org/omim/273800

altLabel

GT

definition

(GT) - A common inherited disease of platelet aggregation. It is characterized by mucocutaneous bleeding of mild-to-moderate severity. GT has been classified clinically into types I and II. In type I, platelets show absence of the glycoprotein IIb-IIIa complexes at their surface and lack fibrinogen and clot retraction capability. In type II, the platelets express the GPIIb-IIIa complex at reduced levels, have detectable amounts of fibrinogen, and have low or moderate clot retraction capability.

id

OMIM:273800

notation

OMIM:273800

prefLabel

Glanzmann thrombasthenia

subClassOf

http://purl.obolibrary.org/obo/OGMS_0000031

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