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Regulation of Transcription Ontology
Last uploaded:
December 4, 2018
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| Preferred Name | Glanzmann thrombasthenia | |
| Synonyms |
GT |
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| Definitions |
(GT) - A common inherited disease of platelet aggregation. It is characterized by mucocutaneous bleeding of mild-to-moderate severity. GT has been classified clinically into types I and II. In type I, platelets show absence of the glycoprotein IIb-IIIa complexes at their surface and lack fibrinogen and clot retraction capability. In type II, the platelets express the GPIIb-IIIa complex at reduced levels, have detectable amounts of fibrinogen, and have low or moderate clot retraction capability. |
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| ID |
http://identifiers.org/omim/273800 |
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| altLabel |
GT
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| definition |
(GT) - A common inherited disease of platelet aggregation. It is characterized by mucocutaneous bleeding of mild-to-moderate severity. GT has been classified clinically into types I and II. In type I, platelets show absence of the glycoprotein IIb-IIIa complexes at their surface and lack fibrinogen and clot retraction capability. In type II, the platelets express the GPIIb-IIIa complex at reduced levels, have detectable amounts of fibrinogen, and have low or moderate clot retraction capability.
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| id |
OMIM:273800
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| notation |
OMIM:273800
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| prefLabel |
Glanzmann thrombasthenia
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| subClassOf |
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