REGN_GO

Last uploaded: January 12, 2023
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Preferred Name

RNA-mediated gene silencing
Synonyms

gene silencing by RNA

RNA-dependent gene silencing
Definitions

A process in which an RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.
ID

http://purl.obolibrary.org/obo/GO_0031047
definition

A process in which an RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.
has_exact_synonym

RNA-dependent gene silencing
has_obo_namespace

biological_process
has_related_synonym

gene silencing by RNA
id

GO:0031047
in_subset

http://purl.obolibrary.org/obo/go#goslim_generic

http://purl.obolibrary.org/obo/go#goslim_drosophila
label

RNA-mediated gene silencing
notation

GO:0031047
prefLabel

RNA-mediated gene silencing
term tracker item

https://github.com/geneontology/go-ontology/issues/22635

https://github.com/geneontology/go-ontology/issues/22202
subClassOf

http://purl.obolibrary.org/obo/GO_0010629
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