Performance Summary Display Ontology

Last uploaded: March 8, 2023
Preferred Name

reagent role

Synonyms
Definitions

(copied from ReO) Reagents are distinguished from instruments or devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique. By contrast, instruments do not participate in a chemical reaction/interaction during the technique. Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not. It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance will realize only one of these roles in the execution of a given assay or technique. For example, taq polymerase can bear a reagent role or an evaluant role. In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated. In regard to the statement that reagents are 'distinct' from the specified outputs of a technique, note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role. For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it. Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique). A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer.

ID

http://purl.obolibrary.org/obo/OBI_0000086

comment

(copied from ReO) Reagents are distinguished from instruments or devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique. By contrast, instruments do not participate in a chemical reaction/interaction during the technique. Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not. It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance will realize only one of these roles in the execution of a given assay or technique. For example, taq polymerase can bear a reagent role or an evaluant role. In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated. In regard to the statement that reagents are 'distinct' from the specified outputs of a technique, note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role. For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it. Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).

alternative term

reagent

curator note

Feb 10, 2009. changes after discussion at OBI Consortium Workshop Feb 2-6, 2009. accepted as core term. May 28 2013. Updated definition taken from ReO based on discussions initiated in Philly 2011 workshop. Former defnition described a narrower view of reagents in chemistry that restricts bearers of the role to be chemical entities ("a role played by a molecular entity used to produce a chemical reaction to detect, measure, or produce other substances"). Updated definition allows for broader view of reagents in the domain of biomedical research to include larger materials that have parts that participate chemically in a molecular reaction or interaction.

definition source

PERSON:Matthew Brush

editor preferred term

reagent role

example of usage

Buffer, dye, a catalyst, a solvating agent.

has curation status

http://purl.obolibrary.org/obo/IAO_0000120

imported from

http://purl.obolibrary.org/obo/obi.owl

label

reagent role

prefixIRI

OBI:0000086

prefLabel

reagent role

term editor

PERSON:Matthew Brush

textual definition

A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer.

subClassOf

http://purl.obolibrary.org/obo/BFO_0000023

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/OBI_0000086 AFO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 IDO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 PDRO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 EUPATH SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 CLO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 OBI SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 INBANCIDO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 CHEAR SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 NGBO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 MS SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 OBCS SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 ONE SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 OPMI SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 OBI_BCGO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 BMS-LM SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 EGO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 OBIB SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 BERO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 AFO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 ONS SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 OLAM SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 HHEAR SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 STATO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 VIVO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 CIDO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 OBI_IEE SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 ICO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 KTAO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 VIDO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 GENO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 OHMI SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 IDO-COVID-19 SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 ERO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 VO SAME_URI
http://purl.obolibrary.org/obo/OBI_0000086 AFO LOOM
http://semanticscience.org/resource/SIO_000893 SIO LOOM
http://uri.neuinfo.org/nif/nifstd/birnlex_11019 NIFSTD LOOM
http://semanticscience.org/resource/SIO_000893 HHEARP LOOM
http://semanticscience.org/resource/SIO_000893 CHEAR LOOM
http://semanticscience.org/resource/SIO_000893 BIOMO LOOM
http://semanticscience.org/resource/SIO_000893 SCO LOOM
http://semanticscience.org/resource/SIO_000893 HHEAR LOOM
http://semanticscience.org/resource/SIO_000893 HASCO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 IDO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 PDRO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 EUPATH LOOM
http://purl.obolibrary.org/obo/OBI_0000086 CLO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 OBI LOOM
http://purl.obolibrary.org/obo/OBI_0000086 INBANCIDO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 CHEAR LOOM
http://purl.obolibrary.org/obo/OBI_0000086 NGBO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 MS LOOM
http://purl.obolibrary.org/obo/OBI_0000086 OBCS LOOM
http://purl.obolibrary.org/obo/OBI_0000086 ONE LOOM
http://purl.obolibrary.org/obo/OBI_0000086 OPMI LOOM
http://purl.obolibrary.org/obo/OBI_0000086 OBI_BCGO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 BMS-LM LOOM
http://purl.obolibrary.org/obo/OBI_0000086 EGO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 OBIB LOOM
http://purl.obolibrary.org/obo/OBI_0000086 BERO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 AFO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 ONS LOOM
http://purl.obolibrary.org/obo/OBI_0000086 OLAM LOOM
http://purl.obolibrary.org/obo/OBI_0000086 HHEAR LOOM
http://purl.obolibrary.org/obo/OBI_0000086 STATO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 CIDO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 OBI_IEE LOOM
http://purl.obolibrary.org/obo/OBI_0000086 ICO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 KTAO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 VIDO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 GENO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 OHMI LOOM
http://purl.obolibrary.org/obo/OBI_0000086 IDO-COVID-19 LOOM
http://purl.obolibrary.org/obo/OBI_0000086 ERO LOOM
http://purl.obolibrary.org/obo/OBI_0000086 VO LOOM
http://purl.org/biotop/biotop.owl#ReagentRole BT LOOM
http://bioontology.org/projects/ontologies/birnlex#birnlex_11019 BIRNLEX LOOM
http://purl.bioontology.org/ontology/npo#NPO_292 NPO LOOM