Protein Ontology

Last uploaded: August 20, 2024
Preferred Name

growth/differentiation factor
Synonyms
Definitions

A TGF-beta-like cystine-knot cytokine that is closely related to the BMP family. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release the bioactive C-terminal peptide. GDFs act as signaling molecules during embryonic tendon/ligament formation. Category=family.

ID

http://purl.obolibrary.org/obo/PR_000000098

comment

Category=family.

definition

A TGF-beta-like cystine-knot cytokine that is closely related to the BMP family. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release the bioactive C-terminal peptide. GDFs act as signaling molecules during embryonic tendon/ligament formation.

has_obo_namespace

protein

id

PR:000000098

label

growth/differentiation factor

notation

PR:000000098

prefLabel

growth/differentiation factor

treeView

http://purl.obolibrary.org/obo/PR_000000008

subClassOf

http://purl.obolibrary.org/obo/PR_000000008

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