Protein Ontology

Last uploaded: August 20, 2024
Preferred Name

bone morphogenetic protein
Synonyms
Definitions

A TGF-beta-like cystine-knot cytokine that is related to the transforming growth factor-beta, anti-Muellerian hormone, and activin/inhibin protein families, which are all involved in the regulation of cell growth and differentiation. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release bioactive the C-terminal peptide. BMP is involved in body patterning and morphogenesis. BMP signals are transmitted through specific type 2 and type 1 receptors. Category=family.

ID

http://purl.obolibrary.org/obo/PR_000000034

comment

Category=family.

database_cross_reference

PIRSF:PIRSF037272

definition

A TGF-beta-like cystine-knot cytokine that is related to the transforming growth factor-beta, anti-Muellerian hormone, and activin/inhibin protein families, which are all involved in the regulation of cell growth and differentiation. These are produced as dimeric precursors and undergo post-translational processing for activation, requiring cleavage to release bioactive the C-terminal peptide. BMP is involved in body patterning and morphogenesis. BMP signals are transmitted through specific type 2 and type 1 receptors.

has_obo_namespace

protein

id

PR:000000034

label

bone morphogenetic protein

notation

PR:000000034

prefLabel

bone morphogenetic protein

treeView

http://purl.obolibrary.org/obo/PR_000000008

subClassOf

http://purl.obolibrary.org/obo/PR_000000008

Delete Subject Author Type Created
No notes to display