Protein Ontology

Last uploaded: August 20, 2024
Preferred Name

Rho-associated protein kinase
Synonyms
Definitions

A protein that is a translation product of an evolutionary-related gene with core domain composition consisting of an N-terminal Protein kinase domain (Pfam:PF00069), a Rho Binding domain (Pfam:PF08912), and a PH domain (Pfam:PF00169) and a Phorbol esters/diacylglycerol binding domain (C1 domain) (Pfam:PF00130) at the C-terminus. Rho-associated protein kinases are mediators of many cellular processes by being effectors of the small GTP-binding protein Rho. Category=family.

ID

http://purl.obolibrary.org/obo/PR_000000024

comment

Category=family.

database_cross_reference

PIRSF:PIRSF037568

definition

A protein that is a translation product of an evolutionary-related gene with core domain composition consisting of an N-terminal Protein kinase domain (Pfam:PF00069), a Rho Binding domain (Pfam:PF08912), and a PH domain (Pfam:PF00169) and a Phorbol esters/diacylglycerol binding domain (C1 domain) (Pfam:PF00130) at the C-terminus. Rho-associated protein kinases are mediators of many cellular processes by being effectors of the small GTP-binding protein Rho.

has_obo_namespace

protein

id

PR:000000024

label

Rho-associated protein kinase

notation

PR:000000024

prefLabel

Rho-associated protein kinase

treeView

http://purl.obolibrary.org/obo/PR_000000001

subClassOf

http://purl.obolibrary.org/obo/PR_000000001

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