Protein Ontology

Last uploaded: November 12, 2025
Id http://purl.obolibrary.org/obo/PR_000000024
http://purl.obolibrary.org/obo/PR_000000024
Preferred Name

Rho-associated protein kinase

Definitions
Category=family. A protein that is a translation product of an evolutionary-related gene with core domain composition consisting of an N-terminal Protein kinase domain (Pfam:PF00069), a Rho Binding domain (Pfam:PF08912), and a PH domain (Pfam:PF00169) and a Phorbol esters/diacylglycerol binding domain (C1 domain) (Pfam:PF00130) at the C-terminus. Rho-associated protein kinases are mediators of many cellular processes by being effectors of the small GTP-binding protein Rho.
Type http://www.w3.org/2002/07/owl#Class
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