PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
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Preferred Name

Negative Regulation Of DNA-binding Transcription Factor Activity
Synonyms
Definitions

"Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:jl]
ID

http://www.phoc.org.cn/pmo/class/PMO_00076789
Database_Cross_Reference

GO:0043433
Definition

"Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:jl]
Gene Annotation

SUFU(UniProtKB:Q9UMX1)

PROX1(UniProtKB:Q92786)

SFRP4(UniProtKB:Q6FHJ7)

PTCH1(UniProtKB:Q13635)

HDAC4(UniProtKB:P56524)

SFRP5(UniProtKB:Q5T4F7)

NR0B2(UniProtKB:Q15466)

KDM1A(UniProtKB:O60341)

POU4F2(UniProtKB:Q12837)

SP100(UniProtKB:P23497)

WFS1(UniProtKB:O76024)

CEBPG(UniProtKB:P53567)

FOXP3(UniProtKB:Q9BZS1)

FOXS1(UniProtKB:O43638)

TCF7L2(UniProtKB:Q9NQB0)

SMAD7(UniProtKB:O15105)

BTRC(UniProtKB:Q9Y297)

ID1(UniProtKB:P41134)

BHLHE40(UniProtKB:O14503)

PIM1(UniProtKB:P11309)

TAF3(UniProtKB:Q5VWG9)

RB1(UniProtKB:P06400)

ESR1(UniProtKB:P03372)

MAD2L2(UniProtKB:Q9UI95)

HAND2(UniProtKB:P61296)

FOXA2(UniProtKB:Q9Y261)

PAXIP1(UniProtKB:Q6ZW49)

FOXH1(UniProtKB:O75593)

ZNF431(UniProtKB:Q8TF32)

MEN1(UniProtKB:O00255)

FZD6(UniProtKB:O60353)

NR0B1(UniProtKB:P51843)

GLIS2(UniProtKB:Q9BZE0)

PEX14(UniProtKB:O75381)

EZH2(UniProtKB:Q15910)

WWP2(UniProtKB:O00308)

CTNNBIP1(UniProtKB:Q9NSA3)

NUPR1(UniProtKB:O60356)

TRIB1(UniProtKB:Q96RU8)

MAP3K10(UniProtKB:Q02779)

SUMO1(UniProtKB:P63165)

RNF2(UniProtKB:Q99496)

EOMES(UniProtKB:O95936)

HDAC2(UniProtKB:Q92769)

HEYL(UniProtKB:Q9NQ87)

FLNA(UniProtKB:P21333)

RLIM(UniProtKB:Q9NVW2)

ID3(UniProtKB:Q02535)

TNFSF4(UniProtKB:P23510)

DDIT3(UniProtKB:P35638)

SIGIRR(UniProtKB:Q6IA17)

PLA2G10(UniProtKB:O15496)

SIRT1(UniProtKB:Q96EB6)

PHB2(UniProtKB:Q99623)

HMOX1(UniProtKB:P09601)

GAS6(UniProtKB:Q14393)

TBX6(UniProtKB:O95947)

HAND1(UniProtKB:O96004)

EGLN1(UniProtKB:Q9GZT9)

XCL1(UniProtKB:P47992)

TBXT(UniProtKB:O15178)

TAF1(UniProtKB:P21675)

KEAP1(UniProtKB:Q14145)

ID2(UniProtKB:Q02363)

PRNP(UniProtKB:P04156)

MED13(UniProtKB:Q9UHV7)

TWIST1(UniProtKB:Q15672)

TNFRSF4(UniProtKB:P43489)
label

Negative Regulation Of DNA-binding Transcription Factor Activity
MCID

MC04807955
PMOID

PMO:00076789
prefixIRI

pmo:PMO_00076789
prefLabel

Negative Regulation Of DNA-binding Transcription Factor Activity
Synonym

"inhibition of transcription factor activity" NARROW []

"down-regulation of transcription factor activity" EXACT []

"down regulation of transcription factor activity" EXACT []

"negative regulation of thyroid hormone receptor activity" NARROW []

"negative regulation of transcription factor activity" BROAD [GOC:dph, GOC:tb]

"negative regulation of androgen receptor activity" NARROW []

"downregulation of transcription factor activity" EXACT []

"negative regulation of sequence-specific DNA binding transcription factor activity" EXACT []

"negative regulation of DNA binding transcription factor activity" EXACT []
Tree Number

T10.1.26.1.33.20.35.2.4.3.1.14.1

T10.1.26.2.9.3

T10.1.26.1.16.8.13.2.3.1.14.1

T10.1.26.1.16.17.17.2.3.1.14.1

T10.1.26.1.16.17.2.4.3.1.14.1

T10.1.26.1.16.17.17.9.1.14.1

T10.1.26.1.16.8.13.9.1.14.1

T10.1.26.2.10.1

T10.1.26.1.16.12.7.2.4.3.1.14.1

T10.1.26.1.16.5.35.2.4.3.1.14.1

T10.1.26.1.16.20.27.2.4.3.1.14.1

T10.1.26.1.33.20.7.52.3.1.14.1

T10.1.26.1.16.5.7.12.1.14.1

T10.1.26.1.1.9

T10.1.26.1.33.20.7.12.1.14.1

T10.1.26.1.16.17.7.1.14.1

T10.1.26.1.16.8.9.52.3.1.14.1

T10.1.26.1.16.8.9.12.1.14.1

T10.1.26.1.16.5.7.52.3.1.14.1
subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00076788

http://www.phoc.org.cn/pmo/class/PMO_00084865

http://www.phoc.org.cn/pmo/class/PMO_00082807
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