PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
Preferred Name

Protein Targeting To ER
Synonyms
Definitions

"The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane." [ISBN:0716731363]

ID

http://www.phoc.org.cn/pmo/class/PMO_00072818

Database_Cross_Reference

GO:0045047

Definition

"The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane." [ISBN:0716731363]

Gene Annotation

PMM2(UniProtKB:O15305)

PMM1(UniProtKB:Q92871)

SRPRA(UniProtKB:P08240)

ZFAND2B(UniProtKB:Q8WV99)

SPCS3(UniProtKB:P61009)

SPCS1(UniProtKB:Q9Y6A9)

SEC61A1(UniProtKB:P61619)

SRP54(UniProtKB:P61011)

SRP14(UniProtKB:P37108)

SPCS2(UniProtKB:Q15005)

SEC61G(UniProtKB:P60059)

label

Protein Targeting To ER

MCID

MC04771893

PMOID

PMO:00072818

prefixIRI

pmo:PMO_00072818

prefLabel

Protein Targeting To ER

Synonym

"protein-endoplasmic reticulum targeting" EXACT []

"protein targeting to endoplasmic reticulum" EXACT []

"protein-ER targeting" EXACT []

Tree Number

T10.1.1.8.2.4.12.2

T10.1.1.2.3.6.12.4.12.2

T10.1.1.4.1.1.12.4.12.2

T10.1.1.2.3.6.12.5.2.2

T10.1.1.4.6.25.5.6

T10.1.1.4.1.1.12.5.2.2

T10.1.1.8.3.3.40.23.2.6.5.6

T10.1.1.8.3.27.42.2.6.5.6

T10.1.1.8.4.3.25.5.6

T10.1.1.2.5.1.12.5.2.2

T10.1.1.8.3.11.25.5.6

T10.1.1.2.3.1.4.12.2

T10.1.1.2.5.1.12.4.12.2

T10.1.1.8.2.1.6.5.6

T10.1.1.2.3.1.1.6.5.6

subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00072817

http://www.phoc.org.cn/pmo/class/PMO_00072943

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