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PMO Precision Medicine Ontology
Last uploaded:
December 16, 2020
| Acronym | PMAPP-PMO |
| Visibility | Public |
| Description | The Precision Medicine Ontology (PMO) has been developed as a standardized ontology for human precision medicine with consistent, reusable and sustainable descriptions of human disease terms, genomic molecular, phenotype characteristics and related medical vocabulary disease concepts through collaborative efforts of researchers at Institute of Medical Information, Chinese Academy of Medical Sciences. The Precision Medicine Ontology focuses on the development of a high level patients-centric ontology for the academic research, thus, it systematically integrates biomedicine vocabularies from GO, NCBI Gene, DrugBank, HPO, MeSH, SNOMED CT, etc. This work is supported by the National Key Research and Development Program of China (Precision Medicine Knowledge Base, Grant No. 2016YFC0901901). |
| Status | Alpha |
| Format | OWL |
| Contact | Jiao Li, li.jiao@imicams.ac.cn Meng Wu, wu.meng@imicams.ac.cn Li Hou, hou.li@imicams.ac.cn |
| Categories | Biomedical Resources |
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| Id | http://www.phoc.org.cn/pmo/class/PMO_00060132
http://www.phoc.org.cn/pmo/class/PMO_00060132
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|---|---|
| Preferred Name | Protein Activation Cascade |
| Definitions |
"A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events." [GOC:add, GOC:mah, GOC:pde]
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label | Protein Activation Cascade
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|---|---|
| prefLabel | Protein Activation Cascade
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| Synonym |
"protein activitory cascade" EXACT [GOC:add]
"protein activation pathway" EXACT [GOC:add]
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| Definition | "A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events." [GOC:add, GOC:mah, GOC:pde]
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| PMOID | PMO:00060132
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| MCID | MC04806429
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| prefixIRI | pmo:PMO_00060132
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| Database_Cross_Reference | GO:0072376
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| Tree Number |
T10.1.13.2
T10.1.14.13.41.40.3
T10.1.14.20.2.3
T10.1.14.13.44.10.3
T10.1.14.8.11.40.3
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| subClassOf | |
| type |
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