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PMO Precision Medicine Ontology
Last uploaded:
December 16, 2020
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Preferred Name | Innate Immune Response | |
Synonyms |
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Definitions |
"Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_15nov05, GOC:mtg_sensu] |
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ID |
http://www.phoc.org.cn/pmo/class/PMO_00055905 |
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Database_Cross_Reference |
GO:0045087
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Definition |
"Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_15nov05, GOC:mtg_sensu]
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Gene Annotation |
IGHV3-23(UniProtKB:P01764) CGAS(UniProtKB:Q8N884) TRBC1(UniProtKB:P01850) IGHV1-58(UniProtKB:A0A0C4DH39) IGHV2-70(UniProtKB:P01814) PSPC1(UniProtKB:Q8WXF1) ADARB1(UniProtKB:P78563) NONO(UniProtKB:Q15233) PPARG(UniProtKB:P37231) SLAMF1(UniProtKB:Q13291) TIFA(UniProtKB:Q96CG3) NCF1(UniProtKB:P14598) SARM1(UniProtKB:Q6SZW1) IGHV4-34(UniProtKB:P06331) IGHV3-21(UniProtKB:A0A0B4J1V1) TRIM32(UniProtKB:Q13049) POLR3D(UniProtKB:P05423) TRIM31(UniProtKB:Q9BZY9) IGHV1-69(UniProtKB:P01742) IL36RN(UniProtKB:Q9UBH0) CAMP(UniProtKB:P49913) S100B(UniProtKB:P04271) IGHV3OR15-7(UniProtKB:A0A075B7D8) PARP9(UniProtKB:Q8IXQ6) FADD(UniProtKB:Q13158) POLR3F(UniProtKB:Q9H1D9) POLR3E(UniProtKB:Q9NVU0) ARHGEF2(UniProtKB:Q92974) DHX9(UniProtKB:Q08211) SIRPB1(UniProtKB:O00241) APOBEC3B(UniProtKB:Q9UH17) PCBP2(UniProtKB:Q15366) IGHV3-9(UniProtKB:P01782) DEFA5(UniProtKB:Q01523) SDHAF4(UniProtKB:Q5VUM1) PPP1R14B(UniProtKB:Q96C90) C4B(UniProtKB:P0C0L5) SUSD4(UniProtKB:Q5VX71) PTX3(UniProtKB:P26022) IRGM(UniProtKB:A1A4Y4) MSRB1(UniProtKB:Q9NZV6) CR2(UniProtKB:P20023) CLEC7A(UniProtKB:Q9BXN2) PYCARD(UniProtKB:Q9ULZ3) TRDC(UniProtKB:B7Z8K6) C1QBP(UniProtKB:Q07021) NOD2(UniProtKB:Q9HC29) CX3CR1(UniProtKB:P49238) ZNF683(UniProtKB:Q8IZ20) C6(UniProtKB:P13671) OPTN(UniProtKB:Q96CV9) IGLC1(UniProtKB:P0CG04) NLRC5(UniProtKB:Q86WI3) RARRES2(UniProtKB:Q99969) BTK(UniProtKB:Q06187) TRIM4(UniProtKB:Q9C037) TRDV2(UniProtKB:A0JD36) IGHV1-69-2(UniProtKB:A0A0G2JMI3) FGR(UniProtKB:P09769) FGB(UniProtKB:P02675) COLEC12(UniProtKB:Q5KU26) DEFB118(UniProtKB:Q96PH6) IFNL2(UniProtKB:Q8IZJ0) TLR9(UniProtKB:Q9NR96) SERINC3(UniProtKB:Q13530) IGHV3-7(UniProtKB:P01780) KIR2DS5(UniProtKB:Q14953) MATR3(UniProtKB:P43243) TRGV9(UniProtKB:Q99603) IGHV7-4-1(UniProtKB:A0A0J9YVY3) CD46(UniProtKB:P15529) KLRD1(UniProtKB:Q13241) IGLC6(UniProtKB:P0CF74) IGHV1OR15-1(UniProtKB:A0A075B7D0) TRIM21(UniProtKB:P19474) TNFRSF14(UniProtKB:Q92956) KIR2DS1(UniProtKB:Q14954) PGLYRP4(UniProtKB:Q96LB8) IGHV3OR16-9(UniProtKB:A0A0B4J2B5) DMBT1(UniProtKB:Q9UGM3) C1R(UniProtKB:P00736) PRKDC(UniProtKB:P78527) SLAMF6(UniProtKB:Q96DU3) IGHV7-81(UniProtKB:A0A0B4J1V7) OTUD4(UniProtKB:Q01804) DEFB115(UniProtKB:Q30KQ5) IGHV4-28(UniProtKB:A0A0C4DH34) IL36G(UniProtKB:Q9NZH8) LGR4(UniProtKB:Q9BXB1) A0A2U3TZJ3(UniProtKB:A0A2U3TZJ3) S100A12(UniProtKB:P80511) CACTIN(UniProtKB:Q8WUQ7) TNFAIP8L2(UniProtKB:Q6P589) AIM2(UniProtKB:O14862) CYBA(UniProtKB:P13498) XRCC6(UniProtKB:P12956) TLR7(UniProtKB:Q9NYK1) IGHV3OR16-13(UniProtKB:A0A075B7E8) DEFB131B(UniProtKB:A0A096LNP1) HAVCR2(UniProtKB:Q8TDQ0) IGHV3-48(UniProtKB:P01763) TRIM62(UniProtKB:Q9BVG3) IGHV3-73(UniProtKB:A0A0B4J1V6) DEFB127(UniProtKB:Q9H1M4) IL27(UniProtKB:Q8NEV9) TREML4(UniProtKB:Q6UXN2) F12(UniProtKB:P00748) CLEC5A(UniProtKB:Q9NY25) IGHV2-5(UniProtKB:P01817) DAB2IP(UniProtKB:Q5VWQ8) TLR5(UniProtKB:O60602) LY9(UniProtKB:Q9HBG7) IL34(UniProtKB:Q6ZMJ4) TRIM14(UniProtKB:Q14142) ELF4(UniProtKB:Q99607) MARCO(UniProtKB:Q9UEW3) DDX1(UniProtKB:Q92499) S4R3C0(UniProtKB:S4R3C0) DHX58(UniProtKB:Q96C10) TRGV8(UniProtKB:A0A0C4DH27) NLRC4(UniProtKB:Q9NPP4) CLU(UniProtKB:P10909) NR1H4(UniProtKB:Q96RI1) ZBTB1(UniProtKB:Q9Y2K1) C1QB(UniProtKB:P02746) SERPING1(UniProtKB:P05155) OTULIN(UniProtKB:Q96BN8) C1QC(UniProtKB:P02747) TRGV5(UniProtKB:A0A0B4J1U4) PJA2(UniProtKB:O43164) IGHV3-20(UniProtKB:A0A0C4DH32) DEFB110(UniProtKB:Q30KQ9) TOLLIP(UniProtKB:Q9H0E2) IGHM(UniProtKB:P01871) PARP14(UniProtKB:Q460N5) CLEC4A(UniProtKB:Q9UMR7) IGHV1-69D(UniProtKB:A0A0B4J2H0) TRIM26(UniProtKB:Q12899) NCF2(UniProtKB:P19878) SSC5D(UniProtKB:A1L4H1) IGHV1-8(UniProtKB:P0DP01) IGHV3-16(UniProtKB:A0A0C4DH30) CSF1R(UniProtKB:P07333) NCR2(UniProtKB:O95944) DEFB107A(UniProtKB:Q8IZN7) IL1RL2(UniProtKB:Q9HB29) CD209(UniProtKB:Q9NNX6) CYBC1(UniProtKB:Q9BQA9) CASP4(UniProtKB:P49662) MIF(UniProtKB:P14174) IGHV3-30-3(UniProtKB:P0DP02) IGLL1(UniProtKB:P15814) TRIM27(UniProtKB:P14373) PRDM1(UniProtKB:O75626) LY86(UniProtKB:O95711) PIK3CG(UniProtKB:P48736) DEFB129(UniProtKB:Q9H1M3) CFI(UniProtKB:P05156) BPIFA1(UniProtKB:Q9NP55) CHGA(UniProtKB:P10645) SRPK1(UniProtKB:Q96SB4) IRF7(UniProtKB:Q92985) KLRG1(UniProtKB:Q96E93) NAIP(UniProtKB:Q13075) C4A(UniProtKB:P0C0L4) NLRP3(UniProtKB:Q96P20) TRIM5(UniProtKB:Q9C035) APOBEC3C(UniProtKB:Q9NRW3) PPP6C(UniProtKB:O00743) POLR3A(UniProtKB:O14802) ANKRD17(UniProtKB:O75179) PYDC2(UniProtKB:Q56P42) IGHV4-31(UniProtKB:P0DP07) SERINC5(UniProtKB:Q86VE9) IGHV3-11(UniProtKB:P01762) SIRT2(UniProtKB:Q8IXJ6) SKP2(UniProtKB:Q13309) A0A0J9YX97(UniProtKB:A0A0J9YX97) IGHV5-10-1(UniProtKB:A0A0J9YXX1) IKBKB(UniProtKB:O14920) CLEC6A(UniProtKB:Q6EIG7) IGHV3-30(UniProtKB:P01768) NOD1(UniProtKB:Q9Y239) PQBP1(UniProtKB:O60828) IGHV1-3(UniProtKB:A0A0C4DH29) CYLD(UniProtKB:Q9NQC7) S100A9(UniProtKB:P06702) IGHV4-30-2(UniProtKB:A0A087WSY4) IGHG4(UniProtKB:P01861) IGHV3-49(UniProtKB:A0A0A0MS15) C4BPB(UniProtKB:P20851) DEFA4(UniProtKB:P12838) DEFB104A(UniProtKB:Q8WTQ1) SIGLEC14(UniProtKB:Q08ET2) IGLC2(UniProtKB:P0DOY2) DEFB108B(UniProtKB:Q8NET1) RBM14(UniProtKB:Q96PK6) LILRA2(UniProtKB:Q8N149) LBP(UniProtKB:P18428) IL1RAP(UniProtKB:Q9NPH3) IFIH1(UniProtKB:Q9BYX4) MID2(UniProtKB:Q9UJV3) NLRP2B(UniProtKB:P0DMW2) KLRC2(UniProtKB:P26717) DDX21(UniProtKB:Q9NR30) CSF1(UniProtKB:P09603) LILRA5(UniProtKB:A6NI73) MALT1(UniProtKB:Q9UDY8) IFI6(UniProtKB:P09912) SIGLEC15(UniProtKB:Q6ZMC9) IGHV1-46(UniProtKB:P01743) TBKBP1(UniProtKB:A7MCY6) CHUK(UniProtKB:O15111) C1QA(UniProtKB:P02745) C1S(UniProtKB:P09871) G3BP1(UniProtKB:Q13283) ZBP1(UniProtKB:Q9H171) CD180(UniProtKB:Q99467) PLA2G2F(UniProtKB:Q9BZM2) FCER1G(UniProtKB:P30273) RNF135(UniProtKB:Q8IUD6) JAK3(UniProtKB:P52333) IGHA2(UniProtKB:P01877) TRBC2(UniProtKB:A0A5B9) IGHE(UniProtKB:P01854) DEFB114(UniProtKB:Q30KQ6) IGHV3-43D(UniProtKB:P0DP04) CLEC4E(UniProtKB:Q9ULY5) DEFB121(UniProtKB:Q5J5C9) IGHV3-38(UniProtKB:A0A0C4DH36) MR1(UniProtKB:Q95460) RNASE3(UniProtKB:P12724) CLEC10A(UniProtKB:Q8IUN9) A0A0C4DH43(UniProtKB:A0A0C4DH43) SH2D1A(UniProtKB:O60880) IGHV3-13(UniProtKB:P01766) TLR10(UniProtKB:Q9BXR5) APOBEC3F(UniProtKB:Q8IUX4) DEFB105A(UniProtKB:Q8NG35) G3BP2(UniProtKB:Q9UN86) DEFB135(UniProtKB:Q30KP9) MFHAS1(UniProtKB:Q9Y4C4) IGHA1(UniProtKB:P01876) F2RL1(UniProtKB:P55085) DEFB133(UniProtKB:Q30KQ1) TMEM173(UniProtKB:Q86WV6) SH2D1B(UniProtKB:O14796) DEFB132(UniProtKB:Q7Z7B7) PIK3CD(UniProtKB:O00329) PGLYRP1(UniProtKB:O75594) DEFB113(UniProtKB:Q30KQ7) ADAR(UniProtKB:P55265) POLR3K(UniProtKB:Q9Y2Y1) LILRA4(UniProtKB:P59901) CR1(UniProtKB:P17927) AGER(UniProtKB:Q15109) MYD88(UniProtKB:Q99836) DDX3X(UniProtKB:O00571) IGHV4OR15-8(UniProtKB:A0A075B7B6) TRIM28(UniProtKB:Q13263) BST2(UniProtKB:Q10589) CYBB(UniProtKB:P04839) APOBEC3G(UniProtKB:Q9HC16) NLRP2(UniProtKB:Q9NX02) IGHV3-53(UniProtKB:P01767) IGHV1-2(UniProtKB:P23083) TIRAP(UniProtKB:P58753) DEFB134(UniProtKB:Q4QY38) APOBEC3H(UniProtKB:Q6NTF7) HMGB3(UniProtKB:O15347) SPON2(UniProtKB:Q9BUD6) PML(UniProtKB:P29590) IGHV4-39(UniProtKB:P01824) TRGV2(UniProtKB:A0A075B6R0) TRIM29(UniProtKB:Q14134) CHID1(UniProtKB:Q9BWS9) IGHV2OR16-5(UniProtKB:A0A0B4J2B6) PSTPIP1(UniProtKB:O43586) CRISP3(UniProtKB:P54108) A0A0J9YY99(UniProtKB:A0A0J9YY99) LGALS3(UniProtKB:P17931) GSDMD(UniProtKB:P57764) TRIM8(UniProtKB:Q9BZR9) SEC14L1(UniProtKB:Q92503) CD6(UniProtKB:P30203) IFI27(UniProtKB:P40305) TRIM35(UniProtKB:Q9UPQ4) TREML1(UniProtKB:Q86YW5) SYK(UniProtKB:P43405) PRKD1(UniProtKB:Q15139) ARID5A(UniProtKB:Q03989) IFNL4(UniProtKB:K9M1U5) IGHV1-18(UniProtKB:A0A0C4DH31) TLR8(UniProtKB:Q9NR97) IKBKG(UniProtKB:Q9Y6K9) AXL(UniProtKB:P30530) S100A7(UniProtKB:P31151) SMPDL3B(UniProtKB:Q92485) POLR3C(UniProtKB:Q9BUI4) APCS(UniProtKB:P02743) TRIM13(UniProtKB:O60858) HMGB2(UniProtKB:P26583) IL23A(UniProtKB:Q9NPF7) MX1(UniProtKB:P20591) POLR3B(UniProtKB:Q9NW08) PYDC1(UniProtKB:Q8WXC3) IL36A(UniProtKB:Q9UHA7) ARG2(UniProtKB:P78540) INAVA(UniProtKB:Q3KP66) SIGLEC16(UniProtKB:A6NMB1) BPIFB3(UniProtKB:P59826) IGHV6-1(UniProtKB:A0A0B4J1U7) TRGV4(UniProtKB:A0A0C4DH28) IGHG3(UniProtKB:P01860) TREM2(UniProtKB:Q9NZC2) KIR2DS2(UniProtKB:P43631) TBK1(UniProtKB:Q9UHD2) LY96(UniProtKB:Q9Y6Y9) IGHV1-24(UniProtKB:A0A0C4DH33) TLR2(UniProtKB:O60603) RIOK3(UniProtKB:O14730) TYROBP(UniProtKB:O43914) SIGLEC10(UniProtKB:Q96LC7) MBL2(UniProtKB:P11226) IGHV3-64(UniProtKB:A0A075B6Q5) PGLYRP3(UniProtKB:Q96LB9) TKFC(UniProtKB:Q3LXA3) ITCH(UniProtKB:Q96J02) TREM1(UniProtKB:Q9NP99) APOBEC3D(UniProtKB:Q96AK3) IGHV3-15(UniProtKB:A0A0B4J1V0) ADAM15(UniProtKB:Q13444) IGLC7(UniProtKB:A0M8Q6) DEFB119(UniProtKB:Q8N690) APOBEC3A(UniProtKB:P31941) IPO7(UniProtKB:O95373) ZCCHC3(UniProtKB:Q9NUD5) IGHV3-30-5(UniProtKB:P0DP03) TRIM23(UniProtKB:P36406) DEFB126(UniProtKB:Q9BYW3) MST1R(UniProtKB:Q04912) DTX3L(UniProtKB:Q8TDB6) ITGAM(UniProtKB:P11215) IGHV1OR15-9(UniProtKB:A0A0B4J2B8) KIR3DS1(UniProtKB:Q14943) IRAK1(UniProtKB:P51617) DEFB131A(UniProtKB:P59861) KIR2DS4(UniProtKB:P43632) TLR1(UniProtKB:Q15399) A0A087WW49(UniProtKB:A0A087WW49) TRIM59(UniProtKB:Q8IWR1) SRPK2(UniProtKB:P78362) CD300E(UniProtKB:Q496F6) IGHV4-30-4(UniProtKB:P0DP06) NLRX1(UniProtKB:Q86UT6) DDX58(UniProtKB:O95786) MAP3K5(UniProtKB:Q99683) HERC5(UniProtKB:Q9UII4) DEFB123(UniProtKB:Q8N688) IGHV4-61(UniProtKB:A0A0C4DH41) A0A0J9YWU9(UniProtKB:A0A0J9YWU9) CD84(UniProtKB:Q9UIB8) RNASE6(UniProtKB:Q93091) TMEM106A(UniProtKB:Q96A25) IGHV3-43(UniProtKB:A0A0B4J1X8) CNPY3(UniProtKB:Q9BT09) ZC3HAV1(UniProtKB:Q7Z2W4) MCOLN2(UniProtKB:Q8IZK6) NRROS(UniProtKB:Q86YC3) B2M(UniProtKB:P61769) CD244(UniProtKB:Q9BZW8) CD1D(UniProtKB:P15813) SAA1(UniProtKB:P0DJI8) TRIM11(UniProtKB:Q96F44) NLRP9(UniProtKB:Q7RTR0) CRP(UniProtKB:P02741) USP14(UniProtKB:P54578) IGHV3-74(UniProtKB:A0A0B4J1X5) EIF2AK2(UniProtKB:P19525) DDX60(UniProtKB:Q8IY21) IFIT5(UniProtKB:Q13325) SFTPD(UniProtKB:P35247) C4BPA(UniProtKB:P04003) IGHV3-72(UniProtKB:A0A0B4J1Y9) ARG1(UniProtKB:P05089) UNC93B1(UniProtKB:Q9H1C4) AKIRIN2(UniProtKB:Q53H80) ECSIT(UniProtKB:Q9BQ95) IL36B(UniProtKB:Q9NZH7) DEFB112(UniProtKB:Q30KQ8) TICAM1(UniProtKB:Q8IUC6) WRNIP1(UniProtKB:Q96S55) APP(UniProtKB:P05067) IGHV1OR21-1(UniProtKB:A0A087WYE8) CD177(UniProtKB:Q8N6Q3) CORO1A(UniProtKB:P31146) RIPK2(UniProtKB:O43353) TARM1(UniProtKB:B6A8C7) DEFB128(UniProtKB:Q7Z7B8) TRIM25(UniProtKB:Q14258) RNASE7(UniProtKB:Q9H1E1) IFI16(UniProtKB:Q16666) BCL10(UniProtKB:O95999) IGKC(UniProtKB:P01834) S100A8(UniProtKB:P05109) CARD9(UniProtKB:Q9H257) NLRP10(UniProtKB:Q86W26) C1RL(UniProtKB:Q9NZP8) CAPZA1(UniProtKB:P52907) IGHV3OR16-12(UniProtKB:A0A075B7B8) DEFB125(UniProtKB:Q8N687) TRDV3(UniProtKB:A0JD37) ILRUN(UniProtKB:Q9H6K1) IGHV3-33(UniProtKB:P01772) IGHV3-66(UniProtKB:A0A0C4DH42) MAVS(UniProtKB:Q7Z434) DEFB116(UniProtKB:Q30KQ4) IGHV1-45(UniProtKB:A0A0A0MS14) JCHAIN(UniProtKB:P01591) RNASE8(UniProtKB:Q8TDE3) CLEC4D(UniProtKB:Q8WXI8) CLEC4C(UniProtKB:Q8WTT0) VNN1(UniProtKB:O95497) TRIM10(UniProtKB:Q9UDY6) IFNL1(UniProtKB:Q8IU54) IGHV3OR16-8(UniProtKB:A0A075B7F1) LYN(UniProtKB:P07948) IGHV4-59(UniProtKB:P01825) CD14(UniProtKB:P08571) ANKHD1(UniProtKB:Q8IWZ3) DEFB106A(UniProtKB:Q8N104) IGHV3-35(UniProtKB:A0A0C4DH35) APOL1(UniProtKB:O14791) MAP4K2(UniProtKB:Q12851) IGHG1(UniProtKB:P01857) TLR6(UniProtKB:Q9Y2C9) TRDV1(UniProtKB:A0A1B0GX56) NLRP6(UniProtKB:P59044) C2(UniProtKB:P06681) NLRP1(UniProtKB:Q9C000) ADGRB1(UniProtKB:O14514) TRGV3(UniProtKB:P03979) POLR3H(UniProtKB:Q9Y535) IGLC3(UniProtKB:P0DOY3) CLEC4M(UniProtKB:Q9H2X3) GPER1(UniProtKB:Q99527) AKAP8(UniProtKB:O43823) TRIL(UniProtKB:Q7L0X0) ANXA1(UniProtKB:P04083) DEFB108A(UniProtKB:A8MXU0) MX2(UniProtKB:P20592) KRT16(UniProtKB:P08779) A0A0J9YW62(UniProtKB:A0A0J9YW62) HLA-E(UniProtKB:P13747) DEFB1(UniProtKB:P60022) CD300LB(UniProtKB:A8K4G0) H0Y858(UniProtKB:H0Y858) SLPI(UniProtKB:P03973) XRCC5(UniProtKB:P13010) HMGB1(UniProtKB:P09429) LCN2(UniProtKB:P80188) FGA(UniProtKB:P02671) IGHV4-38-2(UniProtKB:P0DP08) TRAF3(UniProtKB:Q13114) IGHG2(UniProtKB:P01859) CD55(UniProtKB:P08174) GZMM(UniProtKB:P51124) TRIM15(UniProtKB:Q9C019) CRCP(UniProtKB:O75575) IGHV4-4(UniProtKB:A0A075B6R2) DEFB124(UniProtKB:Q8NES8) PGLYRP2(UniProtKB:Q96PD5) FBXO9(UniProtKB:Q9UK97) IFNL3(UniProtKB:Q8IZI9) IRAK4(UniProtKB:Q9NWZ3) DHX36(UniProtKB:Q9H2U1) HEXIM1(UniProtKB:O94992) PADI4(UniProtKB:Q9UM07) POLR3G(UniProtKB:O15318) IGHD(UniProtKB:P01880) IGLL5(UniProtKB:B9A064) GATA3(UniProtKB:P23771) DCST1(UniProtKB:Q5T197) CAPZA2(UniProtKB:P47755) A0A0J9YX35(UniProtKB:A0A0J9YX35) ALPK1(UniProtKB:Q96QP1) IGHV3OR16-10(UniProtKB:A0A075B7F0) IGHV5-51(UniProtKB:A0A0C4DH38) CD160(UniProtKB:O95971) TLR3(UniProtKB:O15455) SFPQ(UniProtKB:P23246) TICAM2(UniProtKB:Q86XR7) TLR4(UniProtKB:O00206) IGHV2-26(UniProtKB:A0A0B4J1V2)
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label |
Innate Immune Response
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MCID |
MC04771123
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PMOID |
PMO:00055905
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prefixIRI |
pmo:PMO_00055905
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prefLabel |
Innate Immune Response
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Synonym |
"innate immunity" EXACT [GOC:pg] "nonspecific immune response" EXACT []
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Tree Number |
T10.1.13.6.5 T10.1.2.2.11.9 T10.1.13.1.2.3.11.9 T10.1.28.5.5 T10.1.13.5.3.3.11.9 T10.1.13.12.4.5.9
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subClassOf |
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