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PMO Precision Medicine Ontology
Last uploaded:
December 16, 2020
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| Preferred Name | Intermediate Filament | |
| Synonyms |
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| Definitions |
"A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins." [http://www.cytochemistry.net/Cell-biology/intermediate_filaments.htm, ISBN:0198506732] |
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| ID |
http://www.phoc.org.cn/pmo/class/PMO_00054719 |
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| Database_Cross_Reference |
GO:0005882
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| Definition |
"A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins." [http://www.cytochemistry.net/Cell-biology/intermediate_filaments.htm, ISBN:0198506732]
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| Gene Annotation |
KRT40(UniProtKB:Q6A162) KRTAP19-7(UniProtKB:Q3SYF9) KRT28(UniProtKB:Q7Z3Y7) SYNC(UniProtKB:Q9H7C4) KRTAP13-1(UniProtKB:Q8IUC0) KRT25(UniProtKB:Q7Z3Z0) KRT31(UniProtKB:Q15323) SCYGR3(UniProtKB:A0A286YF60) KRT27(UniProtKB:Q7Z3Y8) MACF1(UniProtKB:Q9UPN3) FLG(UniProtKB:P20930) KRT5(UniProtKB:P13647) H3BQV1(UniProtKB:H3BQV1) PKP1(UniProtKB:Q13835) KRTAP17-1(UniProtKB:Q9BYP8) KRT12(UniProtKB:Q99456) KRTAP11-1(UniProtKB:Q8IUC1) KRT24(UniProtKB:Q2M2I5) KRT34(UniProtKB:O76011) KRTAP8-1(UniProtKB:Q8IUC2) KRTAP21-1(UniProtKB:Q3LI58) SCYGR10(UniProtKB:A0A286YEX9) KRTAP22-1(UniProtKB:Q3MIV0) KRTAP13-3(UniProtKB:Q3SY46) SLC1A4(UniProtKB:P43007) KRT19(UniProtKB:P08727) KRTAP19-3(UniProtKB:Q7Z4W3) IFFO2(UniProtKB:Q5TF58) KRTAP20-4(UniProtKB:Q3LI62) KRTAP19-2(UniProtKB:Q3LHN2) NCKIPSD(UniProtKB:Q9NZQ3) LOC100653049(UniProtKB:A0A140TA62) KRTAP20-2(UniProtKB:Q3LI61) KRTAP21-2(UniProtKB:Q3LI59) KRTAP19-4(UniProtKB:Q3LI73) KRT33A(UniProtKB:O76009) KRTAP15-1(UniProtKB:Q3LI76) DSP(UniProtKB:P15924) ADORA2A(UniProtKB:P29274) TLK2(UniProtKB:Q86UE8) NME2(UniProtKB:P22392) MYO5A(UniProtKB:Q9Y4I1) SYNM(UniProtKB:O15061) KRT3(UniProtKB:P12035) EVPLL(UniProtKB:A8MZ36) KRT8(UniProtKB:P05787) KRT20(UniProtKB:P35900) JUP(UniProtKB:P14923) KRT6C(UniProtKB:P48668) PRPH(UniProtKB:P41219) SCYGR5(UniProtKB:A0A286YF46) BFSP2(UniProtKB:Q13515) MICAL1(UniProtKB:Q8TDZ2) KRTAP26-1(UniProtKB:Q6PEX3) SCYGR4(UniProtKB:A0A286YEV6) KRT222(UniProtKB:Q8N1A0) KRTAP6-1(UniProtKB:Q3LI64) KRT39(UniProtKB:Q6A163) IFFO1(UniProtKB:Q0D2I5) KRTAP19-8(UniProtKB:Q3LI54) SCYGR7(UniProtKB:A0A286YF01) KRT35(UniProtKB:Q92764) VIM(UniProtKB:P08670) PKP2(UniProtKB:Q99959) DES(UniProtKB:P17661) EPPK1(UniProtKB:P58107) KRT2(UniProtKB:P35908) SCYGR6(UniProtKB:A0A286YF77) KRT38(UniProtKB:O76015) NES(UniProtKB:P48681) KRTAP19-1(UniProtKB:Q8IUB9) MNS1(UniProtKB:Q8NEH6) KRT15(UniProtKB:P19012) KRT9(UniProtKB:P35527) DST(UniProtKB:Q03001) GJA1(UniProtKB:P17302) KRT18(UniProtKB:P05783) KRT36(UniProtKB:O76013) PPL(UniProtKB:O60437) KRTAP19-5(UniProtKB:Q3LI72) SCYGR8(UniProtKB:A0A286YFG1) LMNTD1(UniProtKB:Q8N9Z9) KRTAP20-3(UniProtKB:Q3LI60) GFAP(UniProtKB:P14136) KRTAP13-4(UniProtKB:Q3LI77) KRTAP23-1(UniProtKB:A1A580) KRT23(UniProtKB:Q9C075) KRT26(UniProtKB:Q7Z3Y9) KRTAP20-1(UniProtKB:Q3LI63) CLIP1(UniProtKB:P30622) PNN(UniProtKB:Q9H307) SCYGR2(UniProtKB:A0A286YFB4) KRT32(UniProtKB:Q14532) KRT33B(UniProtKB:Q14525) KRTAP12-4(UniProtKB:P60329) KRTAP22-2(UniProtKB:Q3LI68) KRT4(UniProtKB:P19013) PLEC(UniProtKB:Q15149) NME1(UniProtKB:P15531) KRTAP6-2(UniProtKB:Q3LI66) KRT76(UniProtKB:Q01546) KRT37(UniProtKB:O76014) KRTAP7-1(UniProtKB:Q8IUC3) KRT14(UniProtKB:P02533) KRT17(UniProtKB:Q04695) KRT16(UniProtKB:P08779) KRT10(UniProtKB:P13645) KRTAP6-3(UniProtKB:Q3LI67) EVPL(UniProtKB:Q92817) KRTAP21-3(UniProtKB:Q3LHN1) KRTAP19-6(UniProtKB:Q3LI70) BFSP1(UniProtKB:Q12934) KRTAP25-1(UniProtKB:Q3LHN0) KRTAP13-2(UniProtKB:Q52LG2) KRT7(UniProtKB:P08729) SCYGR1(UniProtKB:A0A286YEY9) KRT75(UniProtKB:O95678) KRTAP27-1(UniProtKB:Q3LI81)
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| label |
Intermediate Filament
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| MCID |
MC04797576
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| PMOID |
PMO:00054719
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| prefixIRI |
pmo:PMO_00054719
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| prefLabel |
Intermediate Filament
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| Synonym |
"intermediate filament associated protein" RELATED [] "type II intermediate filament associated protein" RELATED [] "type I intermediate filament associated protein" RELATED []
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| Tree Number |
T10.3.14.13.16.12.3 T10.3.7.100.34.16.12.3 T10.3.18.4.2.4.3
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