PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
Preferred Name

Stereocilium
Synonyms
Definitions

"An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles." [GOC:ecd, PMID:15661519, PMID:7840137]

ID

http://www.phoc.org.cn/pmo/class/PMO_00054375

Database_Cross_Reference

GO:0032420

Definition

"An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles." [GOC:ecd, PMID:15661519, PMID:7840137]

Gene Annotation

MYO15A(UniProtKB:Q9UKN7)

FSCN2(UniProtKB:O14926)

MYO7A(UniProtKB:Q13402)

CALB1(UniProtKB:P05937)

PCDH15(UniProtKB:Q96QU1)

PDZD7(UniProtKB:Q9H5P4)

CALB2(UniProtKB:P22676)

ATP8B1(UniProtKB:O43520)

SLC4A7(UniProtKB:Q9Y6M7)

ADCY6(UniProtKB:O43306)

PAFAH1B1(UniProtKB:P43034)

CLRN1(UniProtKB:P58418)

RIPOR2(UniProtKB:Q9Y4F9)

CDH23(UniProtKB:Q9H251)

KPTN(UniProtKB:Q9Y664)

EPS8(UniProtKB:Q12929)

WHRN(UniProtKB:Q9P202)

MPP1(UniProtKB:Q00013)

TWF2(UniProtKB:Q6IBS0)

RDX(UniProtKB:P35241)

USH1C(UniProtKB:Q9Y6N9)

BBS2(UniProtKB:Q9BXC9)

GRXCR2(UniProtKB:A6NFK2)

IFT20(UniProtKB:Q8IY31)

CIB2(UniProtKB:O75838)

LOXHD1(UniProtKB:Q8IVV2)

PVALB(UniProtKB:P20472)

ELMOD3(UniProtKB:Q96FG2)

RHOC(UniProtKB:P08134)

TSPEAR(UniProtKB:Q8WU66)

TPRN(UniProtKB:Q4KMQ1)

GRXCR1(UniProtKB:A8MXD5)

DOCK4(UniProtKB:Q8N1I0)

label

Stereocilium

MCID

MC04773289

PMOID

PMO:00054375

prefixIRI

pmo:PMO_00054375

prefLabel

Stereocilium

Tree Number

T10.3.14.27

T10.3.7.26.6.15.14

T10.3.7.26.6.16.2

T10.3.7.22.30.14

subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00054300

http://www.phoc.org.cn/pmo/class/PMO_00055176

http://www.phoc.org.cn/pmo/class/PMO_00055226

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