PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
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Preferred Name

SAGA-type Complex
Synonyms
Definitions

"A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins." [GOC:mah, PMID:10637607, PMID:17337012]
ID

http://www.phoc.org.cn/pmo/class/PMO_00053526
Database_Cross_Reference

GO:0070461
Definition

"A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins." [GOC:mah, PMID:10637607, PMID:17337012]
Gene Annotation

SUPT20H(UniProtKB:Q8NEM7)

TADA2A(UniProtKB:O75478)

HCFC1(UniProtKB:P51610)

SGF29(UniProtKB:Q96ES7)

TADA2B(UniProtKB:Q86TJ2)

USP22(UniProtKB:Q9UPT9)
label

SAGA-type Complex
MCID

MC04802643
PMOID

PMO:00053526
prefixIRI

pmo:PMO_00053526
prefLabel

SAGA-type Complex
Synonym

"SAGA family complex" EXACT [PMID:17337012]
Tree Number

T10.3.14.13.7.126.25.2

T10.3.9.325.71.43.2.1.2

T10.3.7.100.34.7.126.25.2

T10.3.7.100.51.1.2
subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00053525
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