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PMO Precision Medicine Ontology
Last uploaded:
December 16, 2020
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| Id | http://www.phoc.org.cn/pmo/class/PMO_00051566
http://www.phoc.org.cn/pmo/class/PMO_00051566
|
|---|---|
| Preferred Name | Hemidesmosome |
| Definitions |
"A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces." [GOC:kmv, ISBN:0815316208, PMID:20205195]
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Hemidesmosome
|
|---|---|
| prefLabel |
Hemidesmosome
|
| Gene Annotation |
ITGA6(UniProtKB:P23229)
COL17A1(UniProtKB:Q9UMD9)
ITGB4(UniProtKB:P16144)
JUP(UniProtKB:P14923)
EPPK1(UniProtKB:P58107)
ERBIN(UniProtKB:Q96RT1)
DST(UniProtKB:Q03001)
PLEC(UniProtKB:Q15149)
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|
| Synonym |
"hemi-adherens junction" RELATED [http://www.wormatlas.org/glossaries/hglossary.htm#hemiadherensjunction]
"trans-epithelial attachment" NARROW [GOC:kmv, PMID:20205195]
"epidermal attachment structure" NARROW [GOC:kmv]
"fibrous organelle" NARROW [GOC:kmv, PMID:20205195]
|
| Definition |
"A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces." [GOC:kmv, ISBN:0815316208, PMID:20205195]
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| PMOID |
PMO:00051566
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| MCID |
MC04787292
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| prefixIRI |
pmo:PMO_00051566
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| Database_Cross_Reference |
GO:0030056
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| Tree Number |
T10.3.1.1.2
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| subClassOf | |
| type |
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