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PMO Precision Medicine Ontology
Last uploaded:
December 16, 2020
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| Preferred Name | Membrane Raft | |
| Synonyms |
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| Definitions |
"Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions." [PMID:16645198, PMID:20044567] |
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| ID |
http://www.phoc.org.cn/pmo/class/PMO_00051475 |
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| Database_Cross_Reference |
GO:0045121
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| Definition |
"Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions." [PMID:16645198, PMID:20044567]
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| Gene Annotation |
SDCBP(UniProtKB:O00560) LAMTOR1(UniProtKB:Q6IAA8) CD24(UniProtKB:P25063) SLC25A5(UniProtKB:P05141) KCNE1(UniProtKB:P15382) FADD(UniProtKB:Q13158) CD48(UniProtKB:P09326) MAG(UniProtKB:P20916) DLG1(UniProtKB:Q12959) KCNA5(UniProtKB:P22460) PAG1(UniProtKB:Q9NWQ8) RGMB(UniProtKB:Q6NW40) SULF1(UniProtKB:Q8IWU6) RTN4R(UniProtKB:Q9BZR6) BTK(UniProtKB:Q06187) KCNE3(UniProtKB:Q9Y6H6) KDR(UniProtKB:P35968) CNR1(UniProtKB:P21554) LAX1(UniProtKB:Q8IWV1) LAMP2(UniProtKB:P13473) TNFRSF1B(UniProtKB:P20333) CAV3(UniProtKB:P56539) BIRC2(UniProtKB:Q13490) MLC1(UniProtKB:Q15049) ICAM1(UniProtKB:P05362) PARK7(UniProtKB:Q99497) LRRK2(UniProtKB:Q5S007) LAT(UniProtKB:O43561) STOML3(UniProtKB:Q8TAV4) EGFR(UniProtKB:P00533) CAPN2(UniProtKB:P17655) CD4(UniProtKB:P01730) ADGRG1(UniProtKB:Q9Y653) ARID3A(UniProtKB:Q99856) VDAC1(UniProtKB:P21796) TRADD(UniProtKB:Q15628) SMURF2(UniProtKB:Q9HAU4) SLC9A3R1(UniProtKB:O14745) FAS(UniProtKB:P25445) TEX101(UniProtKB:Q9BY14) PPT1(UniProtKB:P50897) STX12(UniProtKB:Q86Y82) BIRC3(UniProtKB:Q13489) RIPK1(UniProtKB:Q13546) LY6K(UniProtKB:Q17RY6) AHNAK(UniProtKB:Q09666) CD1A(UniProtKB:P06126) TEK(UniProtKB:Q02763) LDHB(UniProtKB:P07195) RTN4RL1(UniProtKB:Q86UN2) IQGAP1(UniProtKB:P46940) CFLAR(UniProtKB:O15519) SHH(UniProtKB:Q15465) SLC34A1(UniProtKB:Q06495) JAK2(UniProtKB:O60674) FURIN(UniProtKB:P09958) ITLN1(UniProtKB:Q8WWA0) ABCB4(UniProtKB:P21439) CASP8(UniProtKB:Q14790) CASP3(UniProtKB:P42574) DPP4(UniProtKB:P27487) GNAI3(UniProtKB:P08754) SERPINH1(UniProtKB:P50454) PDPN(UniProtKB:Q86YL7) RAP1B(UniProtKB:P61224) PGK1(UniProtKB:P00558) CD79A(UniProtKB:P11912) MAL(UniProtKB:P21145) PROM2(UniProtKB:Q8N271) DAPK3(UniProtKB:O43293) PECAM1(UniProtKB:P16284) CNTN1(UniProtKB:Q12860) PPP2R1B(UniProtKB:P30154) P2RX1(UniProtKB:P51575) TUBA1A(UniProtKB:Q71U36) GLIPR1L1(UniProtKB:Q6UWM5) PODXL(UniProtKB:O00592) FYN(UniProtKB:P06241) PTPRC(UniProtKB:P08575) EEF2(UniProtKB:P13639) IKBKB(UniProtKB:O14920) KCNQ1(UniProtKB:P51787) SLC6A3(UniProtKB:Q01959) PPP2CA(UniProtKB:P67775) CAV2(UniProtKB:P51636) BAALC(UniProtKB:Q8WXS3) EFNB1(UniProtKB:P98172) GRIP1(UniProtKB:Q9Y3R0) UNC5B(UniProtKB:Q8IZJ1) CTSD(UniProtKB:P07339) RAB5A(UniProtKB:P20339) ABCA1(UniProtKB:O95477) OLR1(UniProtKB:P78380) RGS19(UniProtKB:P49795) CAVIN1(UniProtKB:Q6NZI2) MYO1C(UniProtKB:O00159) MME(UniProtKB:P08473) CD19(UniProtKB:P15391) TRPC5(UniProtKB:Q9UL62) EPHB1(UniProtKB:P54762) HK1(UniProtKB:P19367) TUBB(UniProtKB:P07437) EFHD2(UniProtKB:Q96C19) ADCY1(UniProtKB:Q08828) CD36(UniProtKB:P16671) CBLC(UniProtKB:Q9ULV8) EDNRB(UniProtKB:P24530) PIKFYVE(UniProtKB:Q9Y2I7) UNC5A(UniProtKB:Q6ZN44) ATP2B1(UniProtKB:P20020) TGFBR2(UniProtKB:P37173) EMP2(UniProtKB:P54851) BST2(UniProtKB:Q10589) ANK2(UniProtKB:Q01484) KCNA3(UniProtKB:P22001) PLLP(UniProtKB:Q9Y342) TUBA1B(UniProtKB:P68363) TNF(UniProtKB:P01375) ORAI1(UniProtKB:Q96D31) CLIP3(UniProtKB:Q96DZ5) ANGPT1(UniProtKB:Q15389) PSEN1(UniProtKB:P49768) SLC9A1(UniProtKB:P19634) ADCY8(UniProtKB:P40145) ITGB1(UniProtKB:P05556) CD2(UniProtKB:P06729) BACE1(UniProtKB:P56817) ADAM17(UniProtKB:P78536) FLOT1(UniProtKB:O75955) PLSCR1(UniProtKB:O15162) OPRD1(UniProtKB:P41143) FAIM2(UniProtKB:Q9BWQ8) INPP5D(UniProtKB:Q92835) STOML2(UniProtKB:Q9UJZ1) DMD(UniProtKB:P11532) SDC4(UniProtKB:P31431) NTSR1(UniProtKB:P30989) TGFBR1(UniProtKB:P36897) LCK(UniProtKB:P06239) TLR2(UniProtKB:O60603) P2RX3(UniProtKB:P56373) GJA1(UniProtKB:P17302) CLN3(UniProtKB:Q13286) RFTN1(UniProtKB:Q14699) FYB2(UniProtKB:Q5VWT5) SLC6A4(UniProtKB:P31645) SLC2A4(UniProtKB:P14672) PTK2B(UniProtKB:Q14289) S100A10(UniProtKB:P60903) GNAI2(UniProtKB:P04899) TLR1(UniProtKB:Q15399) MYADM(UniProtKB:Q96S97) SYNJ2(UniProtKB:O15056) ARC(UniProtKB:Q7LC44) STOM(UniProtKB:P27105) STAT6(UniProtKB:P42226) CAVIN2(UniProtKB:O95810) MALL(UniProtKB:Q13021) ATP7A(UniProtKB:Q04656) PRKAR2B(UniProtKB:P31323) PRKCZ(UniProtKB:Q05513) HYAL2(UniProtKB:Q12891) THY1(UniProtKB:P04216) GHSR(UniProtKB:Q92847) ADCY2(UniProtKB:Q08462) SELE(UniProtKB:P16581) NPC1(UniProtKB:O15118) ITGA1(UniProtKB:P56199) ACE2(UniProtKB:Q9BYF1) KRAS(UniProtKB:P01116) RTN4RL2(UniProtKB:Q86UN3) GNAI1(UniProtKB:P63096) PI4K2A(UniProtKB:Q9BTU6) APP(UniProtKB:P05067) HPSE(UniProtKB:Q9Y251) BSG(UniProtKB:P35613) RHOQ(UniProtKB:P17081) BCL10(UniProtKB:O95999) CXADR(UniProtKB:P78310) CD226(UniProtKB:Q15762) ERLIN2(UniProtKB:O94905) TNFRSF1A(UniProtKB:P19438) NPHS2(UniProtKB:Q9NP85) LYPD6(UniProtKB:Q86Y78) LYN(UniProtKB:P07948) ZAP70(UniProtKB:P43403) PDZK1(UniProtKB:Q5T2W1) CD14(UniProtKB:P08571) DLL1(UniProtKB:O00548) TRAF2(UniProtKB:Q12933) GPC1(UniProtKB:P35052) TLR6(UniProtKB:Q9Y2C9) ANXA2(UniProtKB:P07355) RET(UniProtKB:P07949) CAV1(UniProtKB:Q03135) MAPT(UniProtKB:P10636) LTB4R(UniProtKB:Q15722) CRK(UniProtKB:P46108) ARID3C(UniProtKB:A6NKF2) S1PR1(UniProtKB:P21453) TRPM8(UniProtKB:Q7Z2W7) SORBS1(UniProtKB:Q9BX66) ASAH2(UniProtKB:Q9NR71) GPM6B(UniProtKB:Q13491) AKAP5(UniProtKB:P24588) RIT2(UniProtKB:Q99578) CSK(UniProtKB:P41240) SLC6A2(UniProtKB:P23975) CBLB(UniProtKB:Q13191) CBL(UniProtKB:P22681) CD55(UniProtKB:P08174) NOS1(UniProtKB:P29475) KIRREL1(UniProtKB:Q96J84) STOML1(UniProtKB:Q9UBI4) PRNP(UniProtKB:P04156) TNR(UniProtKB:Q92752) SGCA(UniProtKB:Q16586) TDGF1(UniProtKB:P13385) RAP2B(UniProtKB:P61225) LAT2(UniProtKB:Q9GZY6) OPRM1(UniProtKB:P35372) MAL2(UniProtKB:Q969L2) CARD11(UniProtKB:Q9BXL7)
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| label |
Membrane Raft
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| MCID |
MC04776402
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| PMOID |
PMO:00051475
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| prefixIRI |
pmo:PMO_00051475
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| prefLabel |
Membrane Raft
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| Synonym |
"GEM domain" RELATED [] "lipid raft" EXACT [] "glycolipid-enriched membrane domain" RELATED []
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| Tree Number |
T10.3.2.2.2.1 T10.3.19.3.2.1
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| subClassOf |
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