PLOS Thesaurus

Last uploaded: September 21, 2017

Id	http://localhost/plosthes.2017-1#11754 http://localhost/plosthes.2017-1#11754
Preferred Name	Amyloid proteins
Type	http://www.w3.org/2004/02/skos/core#Concept

prefLabel	Amyloid proteins
homepage	http://journals.plos.org/plosone/browse/amyloid_proteins
related	http://localhost/plosthes.2017-1#11807
type	http://www.w3.org/2004/02/skos/core#Concept http://www.w3.org/2002/07/owl#NamedIndividual
Previous_Classification	10.60.280.50^Amyloid proteins
alpha	Amyloid proteins
scopeNote	Amyloids are insoluble fibrous protein aggregates sharing specific structural traits. They are insoluble and arise from at least 18 inappropriately folded versions of proteins and polypeptides present naturally in the body.[1] These misfolded structures alter their proper configuration such that they erroneously interact with one another or other cell components forming insoluble fibrils. They have been associated with the pathology of more than 20 serious human diseases in that abnormal accumulation of amyloid fibrils in organs may lead to amyloidosis, and may play a role in various neurodegenerative disorders https://en.wikipedia.org/wiki/Amyloid RD
broader	http://localhost/plosthes.2017-1#3597
status	Accepted
Synonym	http://localhost/plosthes.2017-1#T0

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